Senior Cheminformatics Analyst- Chemical Biology and Therapeutics
Senior Cheminformatics Analyst- Chemical Biology and Therapeutics
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$ 78000 - 139360
1 Vacancy
Job Description
This position will work closely with researchers in the Center of Excellence for Data Driven Discovery. The Ideal candidate will work on Projects that will focus on advancing cuttingedge drug discovery programs for childhood catastrophic diseases using the latest approaches in proximitybased targeting. Specifically based on the mechanistic basis of disease our goal is to develop unique chemical approaches (protein degraders synthetic gene regulators and/or functional effectors) to degrade or manipulate targets relevant to pediatric oncology neurodegenerative disorders and sickle cell disease.
The Department of Chemical Biology and Therapeutics is a leader in pioneering research for childhood catastrophic diseases. We are dedicated to advancing drug discovery using the latest in proximitybased targeting and datadriven science. Join our collaborative team where your expertise will directly impact the future of pediatric oncology neurodegenerative disorders and sickle cell disease.
Job Responsibilities:
Analyze biomedical data with minimal supervision by performing advanced analysis algorithm implementation programming and quality check.
Assist senior analysts and scientists in the courses and training with inhouse training programs user groups seminars documentation and newsletters.
Evaluate and integrate products solutions tools and webbased applications.
Assist in the development implementation and maintenance of relevant databases or data warehouse.
Develop prototypes for cloud portals and visualization tools; programs for the analysis of data within databases.
Develop web services to query the database.
Communicate with project managers on design and implementation of analytical processes project progress and results.
Minimum Education and/or Training:
Bachelors degree in bioinformatics cheminformatics statistics/computer science (with a background in biological sciences or chemistry) or related field.
Masters degree or PhD preferred.
Industry experience preferred
Minimum Experience:
Minimum Requirement: 4 years of relevant experience required.
Experience Exception: Masters degree and 1 years of relevant experience.
Experience in at least one programming or scripting language and at least one statistical package with R preferred.
Preferred Technical Expertise:
Proficient in structurebased drug design (SBDD) including small molecule docking pharmacophore modeling virtual screening and molecular dynamics.
Skilled in ligandbased modeling (QSAR conformational analysis) and protein modeling (homology modeling ab initio prediction proteinprotein docking).
Experience with cheminformatics techniques: chemical reaction/library enumeration similarity analysis clustering and dimensionality reduction.
Application of machine learning in drug discovery: target identification drug repurposing virtual screening PK/PD modeling and drugdrug interaction prediction.
Data mining statistical algorithm design and biostatistical analysis.
Ideal Candidate
Team Player:Thrives in a collaborative multidisciplinary environment and enjoys working closely with colleagues from diverse backgrounds.
Multitasker:Demonstrates the ability to manage multiple projects and priorities simultaneously without compromising quality or deadlines.
Flexible:Adapts quickly to shifting project needs new technologies and evolving scientific challenges.
Proactive Communicator:Shares ideas openly seeks feedback and keeps stakeholders informed.
Creative Problem Solver:Approaches challenges with curiosity innovation and a solutionsoriented mindset.
Compensation
In recognition of certain U.S. state and municipal pay transparency laws St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets experience and training licensure and certifications and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $78000 $139360 per year for the role of Senior Cheminformatics Analyst Chemical Biology and Therapeutics.Explore our exceptional benefits!
No Search Firms
St. Jude Childrens Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.
Required Experience:
Senior IC
Employment Type
Full-Time
