Research Scientist, Non-Viral Delivery - Biologics
Research Scientist, Non-Viral Delivery - Biologics
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$ 104200 - 156300
1 Vacancy
Job Description
Job Description
Vertex is seeking a talented Research Scientist to join a collaborative research team focused on nonviral delivery within Vertex Cell and Genetic Therapies (CGT) in Boston MA. The groups mission is to deliver the next generation genetic therapies impacting several therapeutic areas. We are looking for a candidate with a strong desire to deliver innovative new medicines to patients in need. In this labbased role the ideal candidate is strongly experienced in biologics engineering bioconjugation of antibodies and antibodylike scaffolds biologics purification and characterization and structure/function relationships. Prior experience in lipid nanoparticle formulation and biologics discovery are strongly preferred. The candidate should be independent accustomed to taking initiative and bring enthusiasm and intellectual curiosity to Vertexs fastpaced research environment.
Key Responsibilities:
- Work collaboratively amongst several project teams to deliver complex bioconjugates using a variety of conjugation chemistries to a wide set of novel biologic formats
- Develop execute and optimize small and largescale conjugation and purification processes to enable key program milestones
- Develop execute and interpret assays to establish protein and bioconjugate physiochemical properties
- Design engineer characterize fitforpurpose antibody and antibodylike scaffolds
- Structure/function relationships of biologic/target interactions to improve desired characteristics
- Active participation in group and crossdisciplinary project team meetings
Knowledge and Skills:
- Experience working within integrated drug discovery teams
- Handson experience in protein purification (affinity SEC ion exchange TFF) is required
- Experience in biolayer interferometry SPR DLS and HPLCbased characterization methods
- Experience with liposomes lipid nanoparticles or other delivery vehicles
- Track record of productivity as evidenced by a strong publication record
- Selfmotivation organization and ability to communicate effectively
Candidate Requirements:
- Ph.D. with 03 years of relevant protein biochemistry experience. Strong candidates with a BS or MS with extensive relevant experience will also be considered.
Pay Range:
$104200 $156300Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors including skills competencies experience and other jobrelated factors permitted by law.
At Vertex our Total Rewards offerings also include inclusive marketleading benefits to meet our employees wherever they are in their career financial family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical dental and vision benefits to generous paid time off (including a weeklong company shutdown in the Summer and the Winter) educational assistance programs including student loan repayment a generous commuting subsidy matching charitable donations 401(k) and so much more.
Flex Designation:
OnSite DesignatedFlex Eligibility Status:
In this OnSite designated role you will work five days per week onsite with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertexs Policy on Flex @ Vertex Program and may be changed at any time.
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and nondiscrimination for all employees and qualified applicants without regard to a persons race color sex gender identity or expression age religion national origin ancestry ethnicity disability veteran status genetic information sexual orientation marital status or any characteristic protected under applicable law. Vertex is an EVerify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager or contact Talent Acquisition at
Employment Type
Full-Time
