Upstream Development Engineer

The Upstream development engineer will work in the upstream process development team to design execute and optimize consistent fedbatch cell culture processes to produce quality recombinant proteins through laboratory studies. As part of the team they will ensure that these processes are predictable scalable and controlled using multiple sizes of bioreactors (ambr15 ambr250 and benchtop scale bioreactors). The position will support tech transfer of developed and locked cell culture processes to the pilot team and CMOs.

Roles and Responsibilities:

• Conduct upstream process unit operations which include cell banking cell expansion bioreactor process optimization and characterization.
• Work collaboratively within the department as well as crossfunctional peers to execute various upstream studies using shake flasks wave bioreactors and benchtop bioreactors.
• Use high throughput tools such as AMBR15 AMBR250 and Robocolumns as well as analytical tools like cell counters bioanalyzers to support studies.
• Coordinate with the testing team to submit a large number of study samples compiling results received analyzing data using data analysis tools such as Microsoft Excel JMP Spotfire etc. as well as summarizing the findings.
• Document experiments using an electronic lab notebook in addition to supporting technical reports for studies.

Qualifications :

Minimum Qualifications: 

• Bachelors degree in chemistry biology pharmacy or related pharmaceutical science; 24 years relevant industry experience OR
• Bachelors degree in engineering or related discipline; 02 years relevant industry experience OR
• Masters degree in chemistry biology pharmacy engineering or related pharmaceutical science; 02 years relevant industry experience
• Previous experience working in a biologics laboratory or a GMP manufacturing environment
• Experience with mammalian cell culture and aseptic techniques
• experience with benchscale bioreactor operation and other instrumentation that supports cell culture such:
  • Metabolite Analyzers
  • Shake Flasks
  • Cell Culture Plates.
• Authorization to work in the United States indefinitely without restriction or sponsorship

The Ideal Candidate will Have: 

• Experience with harvest filtration and chromatographic separations
• Experience optimizing upstream processes or expression conditions
• Familiarity with additional analytical tools or advanced bioreactor systems
• Experience troubleshooting critical issues or problems and resolving routine issues
• Strong communication skills both verbal and written 
• Strength in organization attention to detail and selfmotivation

Additional Information :

This position is FullTime MondayFriday 8:00 a.m. 5:00 p.m. with overtime as needed and the potential for some offshift hours as depending on the project. Candidates living within a commutable distance of Lexington MA are encouraged to apply.

Excellent fulltime benefits include: 

• comprehensive medical coverage dental and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays

Eurofins Lancaster Laboratories Professional Scientific Services (PSS) is a global awardwinning insourcing solution that places our people at our clients sites dedicated to running and managing laboratory services while eliminating headcount coemployment and projectmanagement worries.

We infuse our 55year track record of scientific and laboratory operations expertise as well as HR and great place to work best practices to recruit hire train and manage highly qualified scientists to perform laboratory services using our clients quality systems and equipment.

To learn more about Eurofins Lancaster Laboratories please explore our website .

Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.

Remote Work :

No

Employment Type :

Fulltime