Sr Scientist I, Molecular Biology
Sr Scientist I, Molecular Biology
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Job Description
Purpose:
Conceive and implement novel experimental approaches to answer scientific questions. Investigate identify develop and optimize new methods and techniques. Contribute to project science in area of expertise. Develop productive collaborations and communications with other groups across science disciplines. We are looking for a Sr. Scientist with a molecular biology background to join our peptide display hit generation team. This role is responsible for developing methods and processes to scale molecular biology workflows for peptide display selection (mRNA and/or PhageDisplay) to many targets and screening conditions by utilizing molecular barcoding strategies laboratory automation and other relevant technologies. This role will also utilize our proprietary peptide microarray platform to aid in accelerating hit identification from peptide display selections.
Responsibilities:
- Lead application of existing mRNADisplay workflows to multiple targets and screening conditions. Includes generation of peptide mRNADisplay libraries designing and carrying out selections against therapeutic targets under multiple conditions preparing nextgeneration sequencing libraries and analyzing the resulting data.
- Lead development of processes and methods to improve efficiency in application of peptide mRNADisplay workflows to multiple targets and screening conditions. Includes utilization of molecular barcoding strategies laboratory automation and other relevant technologies.
- Utilize proprietary data analysis tools to organize data from multiple peptide mRNADisplay screens and analyze multiple datasets to identify pharmaceutically relevant hits.
- Routinely demonstrate scientific initiative and creativity in research or development activities.
- Highly autonomous and productive in performing laboratory research or method development requiring only minimal direction from or interaction with supervisor.
- Formulate conclusions and design followon experiments based on multidisciplinary data.
- May initiate new areas of investigation that are scientifically meaningful reliable and can be incorporated directly into a research or development program.
- A primary author of publications presentations regulatory documents and/or primary inventor of patents.
- Demonstrates high proficiency across a wide range of relevant technologies.
- Maintain a high level of productivity in the lab and/or pilot plant.
- Understand and adhere to corporate standards regarding code of conduct safety appropriate handling of materials controlled drug and radioactive compounds GxP compliance and animal care where applicable.
- Direct mentorship of others.
Qualifications :
- Bachelors Degree or equivalent education and typically 10 years of experience Masters Degree or equivalent education and typically 8 years of experience PhD and no experience necessary.
- Possess thorough theoretical and practical understanding of own scientific discipline.
- Degree(s) should be in Molecular Biology Biochemistry Chemical and Biological Engineering or other relevant fields.
- Training in molecular biology and microbiology methods for the generation and screening of largescale molecular libraries
- Experience in peptide mRNAdisplay including library design and generation library screening and data analysis
- Experience with generating nextgeneration sequencing libraries and analysis of resulting datasets
- Skills in coding for data science (e.g. Python) and/or a willingness to learn
- Experience with laboratory automation and/or molecular barcoding for scaling molecular biology workflows
- Experience in process/project management including prioritization and scheduling of complex laboratory processes.
Additional Information :
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our shortterm incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned vested and determinable. The amount and availability of any bonus commission incentive benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole and absolute discretion unless and until paid and may be modified at the Companys sole and absolute discretion consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
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No
Employment Type :
Fulltime
Employment Type
Full-time
