Senior Scientist I, LC-MS/MS Small Molecule In Vitro/In Vivo Bioanalysis

The NonRegulated Bioanalysis group in the Quantitative Translational & ADME Sciences Department at AbbVie has an open position for a Senior Scientist I position in North Chicago IL to perform small molecule and peptide bioanalysis supporting drug discovery and development. The successful candidate will be responsible for independently conducting quantitative LCMS/MS bioanalysis in support of invivo PK/PD/TK studies along with providing insight and answering technologic or key scientific questions to collaborators and junior scientists.

Responsibilities:

• Perform quantitative LCMS/MS analysis of small molecules and peptides to provide bioanalytical support for PK/PD efficacy and exploratory toxicology studies meeting customer satisfaction and project timelines.
• Routinely operate LCMS/MS instrumentation including maintenance troubleshooting identification and resolution of instrument and assay problems.
• Investigate evaluate and implement new methodologies platforms and technologies to meet challenging assay requirements and throughput while maintaining effective resource utilization.
• Serve as scientific interface and close partner to other teams for bioanalysis support and development/operationalization of novel assays.
• Maintain electronic laboratory notebooks (ELN) and manage study documentation in the Laboratory Information Management System (LIMS).
• Write or contribute to study reports for regulatory submissions. 

Qualifications :

• PhD (04 years) M.S. (8 years) or BS (10 years) in analytical chemistry or related field with relevant academic or industry experience.
• Strong LCMS/MS method development background with direct experience in bioanalysis/assays and understanding of both experimental design and analytical practices required.
• Expertise with current highthroughput LCMS/MS platforms (e.g. Leap autosamplers Sciex API6500/7500 triple quadrupoles) software (e.g. Sciex Analyst and/or OS Electronic notebooks LIMS Discovery Quant) and automated sample preparation (e.g. Hamilton Tecan Dispenser) platforms.
• Working experience in regulated bioanalysis and/or CRO/University Core facility settings will be a plus.
• Excellent personal verbal and written communication skills.
• Highly organized with keen attention to detail enabling effective independent work and success within a matrix team environment.
• Desire to excel in a fastpaced environment with strong problemsolving skills and the ability to prioritize tasks and meet deadlines effectively.

Key Leadership Competencies:

• Build strong relationships with peers and cross functionally with partners outside of the immediate team to enable higher performance proven ability to collaborate successfully across other groups within R&D.
• Creates a learning environment open to suggestions and experiments to drive science in the field of interest.
• Embraces the ideas of others nurtures innovation and manages innovation to reality learns fast grasps the essence and can change course quickly when needed.
• Raises the bar and is never satisfied with the status quo.
• Highly motivated and selfdriven with the flexibility to quickly adapt to different projects.

Additional Information :

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: 

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location and we may ultimately pay more or less than the posted range. This range may be modified in the future.

• We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.

• This job is eligible to participate in our shortterm incentive programs. 

Note: No amount of pay is considered to be wages or compensation until such amount is earned vested and determinable. The amount and availability of any bonus commission incentive benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole and absolute discretion unless and until paid and may be modified at the Companys sole and absolute discretion consistent with applicable law. 

AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. 

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