Scientist, Pharmacokinetics
Scientist, Pharmacokinetics
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Job Description
Job Description
Boston Pharmacokinetics Dynamics Metabolism and Bioanalytics R2 Scientist
At our Company we are inspired by the belief that a researchdriven enterprise dedicated to scientific excellence can create medicines that save and improve employee is building on our proudlegacy of scientific ability to impact the lives of patients worldwide depends on the integrity creativity humility and scientific acumen of our are creating a diverse organization that is inspired by invention and founded on a culture of respect and our Research & Development Division Labs Boston youll have the opportunity to expand your knowledge and skills through collaboration with talented and dedicated colleagues while advancing your career.
The Pharmacokinetics Dynamics Metabolism and Bioanalytics (PDMB) group is seeking a dynamic strategic thinking and collaborative Scientist to contribute to our Companys drug discovery and early clinical development efforts with a focus on labbased bioanalytical efforts for small molecules and peptides. This position will be based at our research labs in Boston MA. Experience utilizing liquidchromatography / mass spectrometry platforms to quantify small molecules and/or peptides from various in vitro and in vivo matrices is required. The ability to develop new bioanalytical methods efficiently utilize data processing platforms and perform basic instrument maintenance is a plus. The position will allow for regular interaction with multidisciplinary discovery project teams and subject matter experts from other functions within our Research & Development Division. The ideal candidate will possess the ability to innovate independently execute and be fully accountable for their scientific deliverables. The candidate will have the opportunity to present their work at departmental meetings as well as promote our Company science through publications and external presentations.
In this exciting position your primary roles will include:
Utilize stateoftheart liquid chromatography/mass spectrometry approaches to quantitate drug levels in various in vitro and in vivo matrices in support of PK and PK/PD efforts
Analyze review and utilize quantitative data to estimate pharmacokinetic parameters in support of multiple programs across various therapeutic areas
Close collaboration with PDMB subjectmatter experts in Boston (MA) South San Francisco (CA) and West Point (PA) aimed at efficiently supporting a dynamic and fastpaced research portfolio
Education Minimum Requirement
Bachelors degree with 3 years relevant laboratory experience or MS degree in biochemistry chemistry pharmacology pharmaceutical sciences biomedical engineering or related field.
Required Experience and Skills
Demonstrated experience utilizing liquidchromatography / mass spectrometry (LC/MS) platforms to quantify small molecules and/or peptides from various in vitro and in vivo matrices
Working knowledge of traditional bioanalytical instrumentation and techniques (primarily LC/MS) including method development optimization and general maintenance
Experience preparing samples from various in vitro and in vivo matrices for bioanalytical characterization including but not limited to protein precipitation liquid/liquid extraction and solidphase extraction techniques.
Strong interpersonal communication problem solving and collaborative qualities to deliver high quality results in a fastpaced environment
Preferred Experience and Skills
Ability to design interpret and troubleshoot experiments aimed at addressing complex questions
Familiarity with electronic laboratory notebooks Watson LIMS and related recordkeeping approaches
Experience working within a researchdriven pharmaceutical company
As an Equal Employment Opportunity Employer we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race color age religion sex sexual orientation gender identity national origin protected veteran status disability status or other applicable legally protected a federal contractor we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws visit:
We are proud to be a company that embraces the value of bringing together talented and committed people with diverse experiences perspectives skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas broad experiences backgrounds and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one anothers thinking and approach problems collectively.
Learn more about your rights including under California Colorado and other US State Acts
Current Employees apply HERE
Current Contingent Workers apply HERE
US and Puerto Rico Residents Only:
Our company is committed to inclusion ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.
As an Equal Employment Opportunity Employer we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race color age religion sex sexual orientation gender identity national origin protected veteran status disability status or other applicable legally protected a federal contractor we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws visit:
We are proud to be a company that embraces the value of bringing together talented and committed people with diverse experiences perspectives skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas broad experiences backgrounds and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one anothers thinking and approach problems collectively.
Learn more about your rights including under California Colorado and other US State Acts
U.S. Hybrid Work Model
Effective September 5 2023 employees in officebased positions in the U.S. will be working a Hybrid work consisting of three total days onsite per week Monday Thursday although the specific days may vary by site or organization with Friday designated as a remoteworking day unless business critical tasks require an onsite Hybrid work model does not apply to and daily inperson attendance is required for fieldbased positions; facilitybased manufacturingbased or researchbased positions where the work to be performed is located at a Company site; positions covered by a collectivebargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note this Hybrid work model guidance also does not apply to roles that have been designated as remote.
San Francisco Residents Only:We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance
Los Angeles Residents Only:We will consider for employment all qualified applicants including those with criminal histories in a manner consistent with the requirements of applicable state and local laws including the City of Los Angeles Fair Chance Initiative for Hiring Ordinance
Search Firm Representatives Please Read Carefully
Merck & Co. Inc. Rahway NJ USA also known as Merck Sharp & Dohme LLC Rahway NJ USA does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no preexisting agreement is in place. Where agency agreements are in place introductions are position specific. Please no phone calls or emails.
Employee Status:
RegularRelocation:
No relocationVISA Sponsorship:
NoTravel Requirements:
No Travel RequiredFlexible Work Arrangements:
Not ApplicableShift:
Not IndicatedValid Driving License:
NoHazardous Material(s):
OEB4 OEB5 Bloodborne pathogensJob Posting End Date:
05/12/2025*A job posting is effective until 11:59:59PM on the day BEFOREthe listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.
Employment Type
Full-Time
