Working ORP Retiree - Staff

University of Colorado Anschutz Medical Campus

Department:Department of Neruosurgery

Job Title: ORP Retiree Staff Position

Position #: Requisition #: 36818

This position is internal to University of Colorado ORP retirees

Job Summary:

Nature of Work

The person in this position will be offered a unique and exciting opportunity to work with a team of neurologists pathologists and neurosurgeons on modern and groundbreaking projects. The lab is focused on finding new treatments and early biomarkers for individuals with Down syndrome Alzheimers disease Traumatic Brain Injuries or Parkinsons disease. Dr. Granholm has collaborations both within CU Anschutz but also with other Universities in the USA and Europe. The applicant will work with human brain tissue human plasma samples and sometimes mice to explore these conditions in a translational manner.

• The applicant will be in charge of a biobank with several sites in the USA and Europe. The role here will be to dissect tissues for spatial transcriptomics immunohistochemistry and exosome extraction and perform experiments together with other scientists at CU in 3 different departments. There is an opportunity to learn human neuroanatomy.
• This is an opportunity to learn new techniques including spatial transcriptomics and advanced imaging techniques.
• The Department of Neurosurgery encompasses several research groups with blended methods and research focus and applications close to the clinic. The day to day work includes working with Pathology Department when there is an autopsy to dissect brain tissue procure tissues for biochemical or morphological studies and collecting and analyzing blood samples from participants with concussions.
• The applicant will function as a lab manager and will have the opportunity to participate in publications as a coauthor and in conferences. The job entails ordering supplies shipping and receiving samples from collaborative labs and communicating with other labs at CU and other universities.
• The focus in the lab is on neurodegenerative disorders and the projects include studying cell replacement therapy in patients with Parkinsons disease finding early biomarkers for Alzheimers disease and Down syndrome and developing new spatial omics techniques together with the Genomics Core at CU.
• Utilize a variety of laboratory techniques required for research projects.
• Prepare human brain for dissection and brain tissue slices for histological processing.
• Routinely conduct assays using molecular and biochemistry techniques such as immunohistochemistry ELISA and Western Blots.
• Support the analytical testing process using standard lab support knowledge in the collection and review of conditions including preserving samples completing sample preparation.
• Prepare lab for daily operations including stocking materials equipment safety cleanliness and related areas.
• Process and analyze blood samples for collaborative studies.
• Provide animal care related to research studies as necessary.
• Dispose of laboratory materials and samples using well established guidelines and instructions and hazardous waste according to CU regulations.
• Data management and data logs (20% effort):
• Review complete and process logs documents databases and related materials and information.
• Research labrelated procedural issues and developing recommendations to resolve process.
• Tabulate and analyze research data. Write data up for publications (coauthorship is available).
• Pick up transport and maintain results samples documents materials and other items as needed.
• Document and communicate results.
• Ship brain tissue samples to other laboratories and receive samples from others.
• Maintain a database for human blood and brain tissues and a freezer inventory.
• Compliance and research conferences and events (10%):
• Ensure compliance with applicable laws rules and regulations; receive guidance and direction or escalate when required.
• Help with IACUC and IRB applications and keep records of CITI and Skillsoft training and procedures in a lab notebook.
• Review and implement lab support policies practices and programs to meet organizational operations and management needs.
• Collaborate with and support Principal Investigators (PI) and other stakeholders with laboratory and research functions.

Professional Field

Staff ORP Retiree

Examples of Work Performed

• Independently and creatively identify laboratory solutions
• Independently Review develop and implement new or modified laboratory techniques required for research projects
• Assist Team Leads Supervisors and/or management with creation and implementation of processes and procedures and quality improvement initiatives
• Assist and train junior team members
• Assist with developing or develop protocolspecific systems and documents including process flows training manuals and Standard Operating Procedures (SOPs). Maintains subject level documentation and prepares documents equipment and/or supplies
• Assist with identifying issues related to operational efficiency and shares results with leadership
• Provide laboratory science expertise and leadership in study design study oversight data management data analysis and manuscript preparation to assist all levels of investigators researchers and clinicians on new research activities across a wide range of disciplines
• Serve as a resource to PIs and other stakeholders

Work Location:

Onsite this role is expected to work onsite and is located in Aurora CO.

Why Join Us:

The Department of Neurosurgery is looking for a full or parttime Professional Research Assistant to join Dr. Lotta Granholms laboratory located at the University of Colorado Anschutz Medical Campus in Aurora CO.

This is an externally funded full or parttime which will assist faculty and staff to reach project goals. The applicant is expected to independently perform histopathology experiments maintain meticulous laboratory records and communicate results and updates to laboratory staff. The Research Assistant will help with ordering and maintaining laboratory supplies and conduct independent experiments on neuropathology neurodegenerative disorders including sectioning and staining of fixed brain tissues and biochemical experiments including exosome isolation from human plasma and blood.

Neurosurgery at CU Anschutz is a dynamic rapidly growing educational enterprise and we are one of the largest Departments of Neurosurgery in the western United States. Currently the department encompasses four teaching institutions: University Hospital Colorado Childrens Hospital Colorado VA Medical Center and Denver Health with all but the latter now located on the new 225acre Anschutz Medical Campus in Aurora CO. The Anschutz Medical Campus is a truly stateoftheart center for education clinical programs and research and innovation. Our current faculty includes 25 Neurosurgeons three NeuroCritical Care Intensivists evergrowing division of Interventional NeuroRadiologists five Neuropsychologists and eight fulltime dedicated research PhDs. The Neurosurgery Department at CU Anschutz is a thriving researchcentered department that promotes translational research at an international level. The research faculty in Neurosurgery are focused welcoming and inclusive and work with the community to inform about severe neurological conditions such as multiple sclerosis Parkinsons disease cancer and Alzheimers disease.

Equal Employment Opportunity Statement:

The University of Colorado (CU) is an Equal Opportunity Employer and complies with all applicable federal state and local laws governing nondiscrimination in employment. We are committed to creating a workplace where all individuals are treated with respect and dignity and we encourage individuals from all backgrounds to apply.

Qualifications:

Minimum Qualifications:

Applicants must meet minimum qualifications at the time of hire.

• Bachelors degree in biology molecular biology cell biology neuroscience including lab experience in these fields
  • A combination of education and related technical/paraprofessional experience may be substituted for the bachelors degree on a year for year basis
• Two (2) years professional level research experience

Preferred Qualifications

• Masters degree in biology molecular biology chemistry genetics or related field
• Three (3) years of experience in an experimental or wet laboratory

Competencies/Knowledge Skills and Abilities:

• Has advanced knowledge of laboratory techniques including safety procedures and techniques
• Ability to communicate effectively both in writing and orally
• Ability to establish and maintain effective working relationships with employees at all levels throughout the institution
• Outstanding customer service skills
• Knowledge of basic human anatomy physiology and medical terminology
• Ability to interpret and master complex research protocol information
• Proficient in Microsoft Office including Excel and Word
• Attention to detail and meticulous record keeping skills
• Strong enthusiasm for science with possibility to gain authorship on scientific manuscripts and present data at conferences

How to Apply:

For full consideration please submit the following document(s):

1. A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position

2. Curriculum vitae / Resume

3. Five professional references including name address phone number (mobile number if appropriate) and email address

Applications are accepted electronically ONLY at

Questions should be directed to: Hayley Tuttle;

Screening of Applications Begins:

Immediately and continues until May 14 2025.

Anticipated Pay Range:

The starting salary range (or hiring range) for this position has been established as HIRING RANGE:

Hiring Range for 0.8 FTE

$66596

The above salary range (or hiring range) represents the Universitys good faith and reasonable estimate of the range of possible compensation at the time of posting. This position is not eligible for overtime compensation unless it is nonexempt.

ADA Statement:

The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act please contact the Human Resources ADA Coordinator at .

Background Check Statement:

The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty staff students and visitors. To assist in achieving that goal we conduct background investigations for all prospective employees.

Vaccination Statement:

CU Anschutz strongly encourages vaccination against the COVID19 virus and othervaccine preventable diseases. If you work visit or volunteer in healthcare facilities or clinics operated by our affiliated hospital or clinical partners or by CU Anschutz you will be required to comply with the vaccination and medical surveillance policies of the facilities or clinics where you work visit or volunteer respectively. In addition if you work in certain research areas or perform certain safety sensitive job duties you must enroll in theoccupational health medical surveillance program.