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Our laboratory conducts 2photon laserscanning microscopy imaging of neuronal activity in awake mice with a focus on mouse models of genetic risks for developing schizophrenia. Preference will be given to applicants who have received their Ph.D. degrees in computational neuroscience physics mathematics computer science or related fields within the last 3 years and have experience in computational neuroscience and data mining using machine learning methods.
The successful candidate will lead an independent research project dedicated to identifying abnormal neuronal activities in circuits of murine models of 22q11.2 and 3q29 deletion syndromes two rare conditions that confer the highest genetic risks of schizophrenia.
Qualifications:
PhD in computational neuroscience physics mathematics computer science or related fields
Demonstrated handson experience with machine learning techniques
Strong programming skills (Python preferred)
Experience analyzing timeseries data preferably from neuroimaging or behavioral studies
Knowledge of signal processing and statistical analysis
Excellent communication skills and ability to work in a collaborative environment
Preference will be given to applicants who have a strong background in leveraging cuttingedge AI and machinelearning techniques to solve complex problems in Neuroscience. The candidate also will benefit from an outstanding highly collaborative work environment in which a diverse team of researchers is focusing efforts toward understanding the mechanisms of schizophrenia and other psychiatric disease behaviors at the levels of neural circuits and individual neurons synapses and molecules.
The laboratory is equipped with two dedicated 2photon mesoscopes (Thorlabs) and Mini2p (Thorlabs). The successful candidate will join a diverse team of researchers whose efforts are directed toward understanding behavior at the levels of neural circuits individual neurons synapses and molecules. The laboratory is part of the Department of Developmental Neurobiology which houses specialized departmental shared resources including an integrated support structure for rodent behavior testing 3dimensional brain organoids in vivo and ex vivo cellular imaging bioinformatics production of genetically engineered animal models singlecell profiling and advanced image processing and analysis. In addition numerous institutional shared resources and core facilities support the laboratory by providing expertise and stateoftheart technologies.
St. Jude Childrens Research Hospital offers an excellent salary and benefits package and is an equal opportunity employer. Interested applicants should send their CVs and the names and addresses of 3 references to:
Stanislav Zakharenko M.D. Ph.D.
Department of Developmental Neurobiology MS 322
St. Jude Childrens Research Hospital
262 Danny Thomas Place
Memphis TN 38105
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Required Experience:
IC
Full-Time