Principal Scientist / Associate Director Translational Informatics
Principal Scientist / Associate Director Translational Informatics
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$ 133970 - 200954
1 Vacancy
Job Description
At AstraZeneca we win through the science it is at the heart of our every success. Every decision is rooted in the limitless possibilities of what science can do. We push the boundaries of science to deliver medicines. This purpose underpins everything we do. It gives us a reason to come to work every day. It reminds us why we exist as a company. It helps us deliver benefits to patients and build new value for shareholders. It also sets the context for our employees activities and the roles of our teams partners and other collaborators. AstraZeneca has a dynamic environment that fosters collaboration and innovation. We attract top minds and we nurture and build top talent.
Introduction to role:
Are you ready to lead the charge in redefining biomedical data into groundbreaking insights We are seeking a visionary Head of Translational Informatics to orchestrate our efforts in integrating multimodal data for biomarker development target discovery and drug repurposing strategies. As a key player in Alexions Bioinformatics and Data Sciences team youll drive innovation through AI/ML bioinformatics and realworld data applications. Join a highimpact team renowned for strategic value and collaboration across the organization. Your success will hinge on strong crossfunctional partnerships using diverse scientific expertise to deliver transformative insights.
Accountabilities:
Lead the Translational Informatics function and craft a coordinated data strategy for biomarker discovery patient stratification and therapeutic insights.
Collaborate with preclinical and clinical teams to translate omics preclinical and clinical data into actionable hypotheses.
Craft and develop AI/ML models for target discovery/prioritization drug repurposing and predictive analytics.
Forge robust collaborations across research clinical regulatory and commercial teams to align informatics strategies with business goals.
Represent the company in external scientific forums and consortia to remain at the forefront of informatics and translational science.
Stay abreast of scientific literature and integrate new insights into research activities and evaluation of new technologies and methods.
Essential Skills/Experience:
PhD (or equivalent) in Bioinformatics Computational Biology AI/ML Genomics Systems Biology Biomedical Informatics or related field.
Minimum 5 years of experience in pharma biotech or academia with a focus on translational research and informatics.
Solid understanding of human genetics molecular biology as well as biological pathways and networks.
Deep expertise in AI/ML methods particularly in biomedical data analysis and model interpretation.
Experience in drug repurposing using computational or integrative approaches.
Handson experience working with multiomics datasets clinical trial data and realworld data (RWD).
Excellent communication and presentation skills with specific experience in crossfunctional collaborations.
Desirable Skills/Experience:
Prior involvement in rare diseases therapeutic areas is advantageous.
Understanding of knowledge graphs network biology or causal inference is a plus.
Experience working with clinical data including data integration curation and analysis of patientlevel datasets is desirable.
When we put unexpected teams in the same room we unleash bold thinking with the power to inspire lifechanging medicines. Inperson working gives us the platform we need to connect work at pace and challenge perceptions. Thats why we work on average a minimum of three days per week from the office. But that doesnt mean were not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
The annual base pay for this position ranges from $133970 to $200954. Hourly and salaried nonexempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors including market location jobrelated knowledge skills and experience. In addition our positions offer a shortterm incentive bonus opportunity; eligibility to participate in our equitybased longterm incentive program (salaried roles) to receive a retirement contribution (hourly roles) and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program 401(k) plan; paid vacation and holidays; paid leaves; and health benefits including medical prescription drug dental and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired employee will be in an atwill position and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time including for reasons related to individual performance Company or individual department/team performance and market factors.
At AstraZeneca we embrace an ethos where work isnt ordinary. Our closeness to patients brings us closer to our mission and each other. With a rapidly expanding portfolio we offer an entrepreneurial spirit combined with the strength of a global biopharma. Here diversity is valued and inclusion is championed fostering an environment where lifechanging ideas can emerge from anywhere. Our culture celebrates integrity innovation and connection to patients lived experiences. Join us to make a difference where it truly counts.
Ready to make an impact Apply now and be part of our journey to transform lives!
Date Posted
01May2025Closing Date
Alexion is proud to be an Equal Employment Opportunity and Affirmative Action employer. We are committed to fostering a culture of belonging where every single person can belong because of their uniqueness. The Company will not make decisions about employment training compensation promotion and other terms and conditions of employment based on race color religion creed or lack thereof sex sexual orientation age ancestry national origin ethnicity citizenship status marital status pregnancy (including childbirth breastfeeding or related medical conditions) parental status (including adoption or surrogacy) military status protected veteran status disability medical condition gender identity or expression genetic information mental illness or other characteristics protected by law. Alexion provides reasonable accommodations to meet the needs of candidates and employees. To begin an interactive dialogue with Alexion regarding an accommodation please contact Alexion participates in EVerify.Required Experience:
Director
Employment Type
Full-Time
