drjobs Senior Scientist BioDesign BioTherapeutics Discovery

Senior Scientist BioDesign BioTherapeutics Discovery

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1 Vacancy
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Job Location drjobs

Cambridge - USA

Monthly Salary drjobs

Not Disclosed

drjobs

Salary Not Disclosed

Vacancy

1 Vacancy

Job Description

About This Role

The Senior Scientist role in the Biotherapeutics Discovery and Delivery group within BioDesign will collaborate closely with CROs and external partners to deliver highquality therapeutic candidates efficiently. Leveraging expertise in antibody engineering principles structure and characterization you will strategically guide antibody discovery and optimization. This role also involves designing and developing antibodyoligonucleotide and protein fusion therapeutics utilizing machine learning techniques for hit triage lead optimization and identification of sequence liabilities. Extensive crossfunctional collaboration is essential for advancing novel antibody therapeutics into the pipeline. Your strategic vision innovation focus and effective will significantly impact Biogens biologics capabilities.

What Youll Do

  • Manage external antibody discovery through CROs and collaborative partnerships
  • Strategically apply antibody engineering and optimization approaches
  • Conduct antibody developability assessments
  • Collaborate with internal and external partners with machine learning expertise to apply ML strategies for hit triage lead optimization and identifying sequence liabilities
  • Design and develop antibodyoligonucleotide and protein fusion therapeutics
  • Oversee project timelines and deliverables to ensure highquality therapeutic antibody candidates
  • Lead crossfunctional teams to integrate antibody discoveries into pipeline programs
  • Identify and implement strategic innovations within antibody discovery and engineering
  • Interpret and oversee analysis of singlecell technology data (e.g. 10x Genomics)
  • Maintain clear effective communication with internal stakeholders and external collaborators
  • Ensure thorough antibody characterization and rigorous quality control

Who You Are

You are a strategic thinker with deep expertise in antibody structure engineering and characterization passionate about collaborating externally and driving therapeutic innovations. You excel in crossfunctional leadership and have a proven track record of advancing complex biologics from discovery to the pipeline.


Qualifications :

Required Skills

  • Ph.D. in biochemistry chemical biology or a related field with 25 years experience or a Masters degree with 68 years relevant industry experience.
  • Proven experience managing antibody discovery through external partnerships (CROs)
  • Deep expertise in antibody developability assessment and engineering
  • Proficiency with machine learning methods for antibody optimization hit triage and sequence liability evaluation
  • Experience in designing antibodyoligonucleotide or protein fusion therapeutics
  • Strong project management skills for delivering highquality candidates on schedule
  • Excellent communication skills for effective collaboration internally and externally
  • Broad knowledge of antibody applications in therapeutic pipeline development

Preferred Skills

  • Experience with singlecell technologies 10x Genomics) and/or display platforms (yeast).
  • Familiarity with biologics data management and integration platforms
  • Experience developing complex biologics such as bispecific antibodies fusion proteins or engineered scaffolds.


Additional Information :

The base salary range for this position is $122000 $163000. Base salary offered is determined though an analytical approach utilizing a combination of factors including but not limited to relevant skills & experience job location and internal equity.  Regular employees are eligible to receive both short term and longterm incentives including cash bonus and equity incentive opportunities designed to reward recent achievements and recognize your future potential based on individual business unit and company performance.   

In addition to compensation Biogen offers a full and highly competitive range of benefits designed to support our employees and their families physical financial emotional and social wellbeing; including but not limited to:  

  • Medical Dental Vision & Life insurances 
  • Fitness & Wellness programs including a fitness reimbursement   
  • Short and LongTerm Disability insurance  
  • A minimum of 15 days of paid vacation and an additional endofyear shutdown time off (Dec 26Dec 31 
  • Up to 12 company paid holidays 3 days off for Personal Significance 
  • 80 hours of sick time per calendar year
  • Paid Maternity and Parental Leave benefit 
  • 401(k) program participation with company matched contributions 
  • Employee stock purchase plan   
  • Tuition reimbursement of up to $10000 per calendar year   
  • Employee Resource Groups participation   

Why Biogen

We are a global team with a commitment to excellence and a pioneering spirit. As a midsized biotechnology company we provide the stability and resources of a wellestablished business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning growth and expanding their skills. Above all we work together to deliver lifechanging medicines with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.

At Biogen we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds cultures and perspectives make us a stronger and more innovative company and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about our DE&I efforts.

All qualified applicants will receive consideration for employment without regard to sex gender identity or expression sexual orientation marital status race color national origin ancestry ethnicity religion age veteran status disability genetic information or any other basis protected by federal state or local law. Biogen is an EVerify Employer in the United States.

 


Remote Work :

No


Employment Type :

Fulltime

Employment Type

Full-time

About Company

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