Biologics Process RD Senior Scientist
Biologics Process RD Senior Scientist
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$ 114700 - 180500
1 Vacancy
Job Description
Job Description
Our Research Scientists are our Inventors. Using innovative thinking stateoftheart facilities and robust scientific methodology we partner to deliver the next medical breakthrough.
Biologics Process Research & Development (BPR&D) within our Research Laboratories is on a mission to rapidly deliver diverse biotherapeutics to patients by efficiently developing innovative robust manufacturing processes and technologies. To achieve this we work closely with colleagues in Discovery Preclinical Early Development Analytical Formulation and Commercial Manufacturing while providing a diverse and inclusive environment for all. Beyond process development for pipeline biologics we innovate and build next generation biomanufacturing technologies. Examples include investments for development of continuous manufacturing green and sustainable processes and proprietary technology platforms. We actively publish and engage with the scientific community to influence the field.
BPR&D includes three labfacing technical functional areas: Process Cell Sciences (PCS) Upstream and Downstream Process Development & Engineering. The latter two together form our Biologics Process Development (BPD) group. This job posting covers opportunities for the BPD group. We are actively looking for highly motivated people with a passion for innovation and interest in contributing to upstream and/or downstream bioprocessing.
Responsibilities include but are not limited to:
Innovation
Develop innovative and disruptive technologies for nextgeneration biologic manufacturing processes.
Apply rigorous scientific principles and data analyses to solve challenging problems related to developing robust costeffective processes.
Experimental Design and ProblemSolving
Develop and characterize robust processes for delivering multikilogram quantities of lifechanging medicines.
Design and conduct lab and/or pilotscale studies to support mechanistic understanding scaleup and transfer of processes to manufacturing.
Collaboration and effective communication:
Work with a collaborative crossfunctional team of talented scientists and engineers to advance the biologics pipeline from early to latestage development.
Partner with groups in both research and manufacturing divisions
Represent your functional area in crossfunctional teams.
Coaching and Mentoring
Train and mentor junior scientists in experimental design and data interpretation
Safety and Compliance
Contribute to a safe and compliant laboratory work environment.
MINIMUM EDUCATION REQUIREMENTS:
- B.S. with 4 years or M.S. with 3 years or PhD with 0 years of relevant experience (or expected PhD graduation within 6 months from date of application) in Chemical Engineering Biochemical Engineering Biomedical Engineering Biotechnology Biochemistry Biology Microbiology or related fields
REQUIRED EXPERIENCE AND SKILLS:
A proven ability to design and execute handson lab and/or in silico experiments.
Proficiency with statistical design and analysis tools
Excellent communication skills ability to work in matrixed teams and collaborate with diverse partners crossfunctionally.
A demonstrated ability to think critically with excellent problem solving and troubleshooting skills.
In addition to the required skillsets above relevant experience is needed in either upstream and/or downstream bioprocessing as described below.
Upstream
Knowledge of recombinant protein expression metabolic pathways biochemistry and cell culture
Understanding of basic bioreactor principles mass transfer kinetics
Understanding of cell & molecular biology
Downstream
Sound scientific knowledge of protein properties and purification.
Understanding of unit operations such as chromatography filtration crystallization precipitation adsorption mixing etc.
PREFERRED EXPERIENCE AND SKILLS:
History of external presentations and/or publications in peerreviewed journals
Data science modeling machine learning and artificial intelligence; proficiency with programming languages
Evaluating and introducing novel technologies and analytical tools in process development and manufacturing
Knowledge of protein biochemistry biophysics conjugation techniques
Vector construction Genetic Engineering and Systems Biology
Knowledge of cellline development for protein expression in mammalian systems and suspension cell culture
Handson experience with RNA and wholegenome (re)sequencing and bioinformatics analysis
High throughput experimentation using automation platforms.
Familiarity with feed and media development for largescale recombinant protein expression in mammalian systems
Knowledge of Quality by Design Process Characterization and Control Strategy development
As an Equal Employment Opportunity Employer we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race color age religion sex sexual orientation gender identity national origin protected veteran status disability status or other applicable legally protected a federal contractor we comply with all affirmative action requirements for protected veterans and individuals with disabilities.
For more information about personal rights under the U.S. Equal Opportunity Employment laws visit:
We are proud to be a company that embraces the value of bringing together talented and committed people with diverse experiences perspectives skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas broad experiences backgrounds and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one anothers thinking and approach problems collectively.
Learn more about your rights including under California Colorado and other US State Acts
#BPRD #PRD #EligibleforERP
Current Employees apply HERE
Current Contingent Workers apply HERE
US and Puerto Rico Residents Only:
Our company is committed to inclusion ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.
As an Equal Employment Opportunity Employer we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race color age religion sex sexual orientation gender identity national origin protected veteran status disability status or other applicable legally protected a federal contractor we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws visit:
We are proud to be a company that embraces the value of bringing together talented and committed people with diverse experiences perspectives skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas broad experiences backgrounds and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one anothers thinking and approach problems collectively.
Learn more about your rights including under California Colorado and other US State Acts
U.S. Hybrid Work Model
Effective September 5 2023 employees in officebased positions in the U.S. will be working a Hybrid work consisting of three total days onsite per week Monday Thursday although the specific days may vary by site or organization with Friday designated as a remoteworking day unless business critical tasks require an onsite Hybrid work model does not apply to and daily inperson attendance is required for fieldbased positions; facilitybased manufacturingbased or researchbased positions where the work to be performed is located at a Company site; positions covered by a collectivebargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note this Hybrid work model guidance also does not apply to roles that have been designated as remote.
The Company is required to provide a reasonable estimate of the salary range for this job in certain states and cities within the United States. Final determinations with respect to salary will take into account a number of factors which may include but not be limited to the primary work location and the chosen candidates relevant skills experience and education.
Expected US salary range:
$114700.00 $180500.00Available benefits include bonus eligibility long term incentive if applicable health care and other insurance benefits (for employee and family) retirement benefits paid holidays vacation and sick days. A summary of benefits is listed here.
San Francisco Residents Only:We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance
Los Angeles Residents Only:We will consider for employment all qualified applicants including those with criminal histories in a manner consistent with the requirements of applicable state and local laws including the City of Los Angeles Fair Chance Initiative for Hiring Ordinance
Search Firm Representatives Please Read Carefully
Merck & Co. Inc. Rahway NJ USA also known as Merck Sharp & Dohme LLC Rahway NJ USA does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no preexisting agreement is in place. Where agency agreements are in place introductions are position specific. Please no phone calls or emails.
Employee Status:
RegularRelocation:
DomesticVISA Sponsorship:
YesTravel Requirements:
10Flexible Work Arrangements:
Not ApplicableShift:
Not IndicatedValid Driving License:
NoHazardous Material(s):
n/aJob Posting End Date:
04/30/2025*A job posting is effective until 11:59:59PM on the day BEFOREthe listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.
Required Experience:
Senior IC
Employment Type
Full-Time
