Research Scientist II - Radiochemist 80-100
Research Scientist II - Radiochemist 80-100
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Job Description
Job Description Summary
Location: Basel SwitzerlandFull time onsite #LIOnsite
At Novartis we are reimagining medicine to improve and extend peoples lives. We use innovative science and technology to address some of societys most challenging healthcare issues. We discover and develop breakthrough treatments and find new ways to deliver them to as many people as possible. How can we continue to advance our science to help patients in need We believe the answers are found when curious courageous and collaborative people are empowered to ask new questions make bolder decisions and take smarter risks.
In Global Discovery Chemistry (GDC) in Basel Switzerland we are at the core of Novartis purpose. We are looking for a highly motivated passionate researcher with a strong scientific background in radiochemistry a curious mindset and cultural agility to work in a highly dynamic team to identify new targeting vectors for radioligand therapies (RLT). Join us and help reimagine medicine!
Job Description
Your responsibilities will include but are not limited to:
You will independently plan and execute the synthesis of radioligands (low molecular weight (LMW) peptide and/or protein vectors) with various radionuclides (Lu177 Ga68 and F18 as part of a dynamic team of radiochemists according to a program defined by the project team.
You will propose evaluate interpret and validate new radiolabeling procedures with radioisotopes including the use of automation and advanced formulation development.
You will collect and perform the quality control of radioligands by High Performance Liquid Chromatography (HPLC) Thin Layer Chromatography (TLC) and Size Exclusion Chromatography (SEC) in the radiochemistry lab environment and release the radioligands for in vitro and in vivo preclinical studies.
You will be responsible for following implemented radiation safety regulations (e.g. trainings dosimetry release and disposal of radioactive waste).
You will evaluate novel technologies including possibilities for automation to increase daily work efficiency.
You will collaboratively work with pharmacologists cell biologists and project teams to characterize novel radioligand therapies in the upsurging oncology disease area.
Minimum requirements
What you will bring to the role:
A passion for handson chemistry experimentation in the laboratory with the ability to critically interpret results build new experimental hypotheses and take smart decisions.
A bachelors degree or apprenticeship in chemistry pharmacy or related discipline with previous experience in radiochemistry and radiolabeling techniques. Please note that this position does not require a PhD.
Must have a minimum of 23 years practical experience in radiochemistry experimentation in the laboratory including working with Radiometals
Comprehensive knowledge of standard IT applications (e.g. ENotebook ChemDraw softwarecontrolled lab equipment).
Experience in the use of automated synthesizer for production and purification of radiolabeled molecules is an asset.
A mindset of curiosity creativity collaboration and openness to diverse thinking with an enthusiasm to develop yourself also beyond your current comfort zones.
An organized working style eye for detail flexibility and commitment to high quality.
A desire to collaborate with a highly dynamic team discuss science and contribute to the next generation of RLTs.
Good oral and written communication in English.
Accessibility and accommodation:
Novartis is committed to working with and providing reasonable accommodation to all individuals. If because of a medical condition or disability you need a reasonable accommodation for any part of the recruitment process or in order to receive more detailed information about the essential functions of a position please send an email to and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
*Please note that restrictions on flexible working may apply and will be discussed at interview stage if applicable
Skills Desired
Analytical Chemistry Automation Systems Collaboration Communication Skills R&D (Research And Development) Radiochemistry Research Science Team PlayerEmployment Type
Full-Time
