Sr Scientist I Biologics Discovery Antibody Engineering
Sr Scientist I Biologics Discovery Antibody Engineering
Employer Active
Job Alert
You will be updated with latest job alerts via email
Share
Job Alert
You will be updated with latest job alerts via email
Not Disclosed
Salary Not Disclosed
1 Vacancy
Job Description
The Biologics and Genetic Medicine group at AbbVie Bay Area is seeking a highly motivated Senior Scientist to join a dynamic team supporting Biologics drug discovery. This position will impact projects through the discovery and engineering of biopharmaceutical products. The ideal candidate should have direct experience with molecular techniques and binding assays (e.g. ELISA or Octet) in vitro display technologies (e.g phage display yeast display) experience with antibody engineering and familiarity with sequence analysis tools and molecular modeling software. The applicant should be highly autonomousconceiving and implementing novel experimental approaches to answer scientific questions. She/he should possess excellent communication skills and be comfortable serving as Biologics Lead in project team settings.
Responsibilities
- Lead from the lab by executing antibody phage library panning and yeast display for antibody discovery and engineering campaigns
- Design execute and troubleshoot molecular biology workflows
- Stay abreast of current literature to continuously innovate and optimize existing workflows
- Serve as Biologics Lead in project team meetings: effectively partner with functional and therapeutic areas to achieve project objectives
Qualifications :
- Bachelors Degree or equivalent education and typically 10 years of experience Masters Degree or equivalent education and typically 8 years of experience PhD and no experience necessary
- Demonstrated ability to use and design in vitro antibody discovery display technologies (e.g. phage yeast display) for discovery and/or engineering
- Experience in antibody engineering and optimization (e.g. humanization affinity maturation)
- Strong molecular biology skills: PCR DNA/RNA isolation plasmid prep gel extraction cloning
- Direct experience with ELISA binding assays
- Sanger sequence analysis experience
- Understanding of protein structure and function
- Excellent organizational skills and the ability to manage multiple projects simultaneously
- Team player with the ability to operate in a fastpaced multidisciplinary environment
- Adapt to rapid changes in project priorities and timelines
- Competency with MS Excel Powerpoint Word
Preferred:
- Direct experience with Octet BLI and flow cytometry
- Knowledgeable in recombinant protein production and characterization
- Proficiency in GraphPad Prism Geneious and Genedata
- Structurebased molecular modeling and applications with AI/ML and integrating complex datasets to drive databased decisions
Additional Information :
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our shortterm incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned vested and determinable. The amount and availability of any bonus commission incentive benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole and absolute discretion unless and until paid and may be modified at the Companys sole and absolute discretion consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only to learn more visit & Puerto Rico applicants seeking a reasonable accommodation click here to learn more:
No
Employment Type :
Fulltime
Employment Type
Full-time
