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Were here for one reason and one reason only to cure cancer. Every moment is dedicated to developing treatments and every action moves us one step closer to our goal. Weve made incredible scientific breakthroughs and our pioneering personalized CAR Tcell therapies have changed the paradigm. But were not finished yet.
Join Kite as we make even bigger advances in cancer therapies and help shape where our business and medical science goes next.
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We are seeking a highly motivated and experienced Scientist to join our team in the field of cellular biology and lipid nanoparticle research. The successful candidate will be responsible for designing executing and analyzing experiments related to the development and characterization of lipid nanoparticlebased and other delivery systems for therapeutic applications.
Responsibilities:
Design and conduct experiments to develop and optimize lipid nanoparticle formulations for the delivery of nucleic acids (e.g. siRNA mRNA) or small molecule .
Perform molecular biology techniques such as mRNA synthesis and processing gene expression analysis (e.g. qPCR flow cytometry) and cellbased assays to evaluate the efficacy and mechanisms of action of lipid nanoparticle formulations.
Characterize lipid nanoparticles using various analytical techniques. The assays may include dynamic light scattering (DLS) zeta potential measurements and transmission electron microscopy (TEM).
Develop and optimize protocols for the synthesis purification and analysis of lipid nanoparticles.
Maintain detailed and accurate records of experimental procedures data and results in laboratory notebooks and electronic databases.
Analyze and interpret experimental data and present findings in team meetings and scientific conferences.
Collaborate with crossfunctional teams including chemists biologists and computational scientists to advance the development of lipid nanoparticlebased therapeutics.
Contribute to the preparation of scientific reports manuscripts and patent applications.
Ensure compliance with laboratory safety protocols good laboratory practices (GLP) and regulatory guidelines.
Basic Qualifications:
PhD degree in Molecular Biology Biochemistry Bioengineering or a related field with a strong background in lipid nanoparticle research and drug delivery systems OR
Masters degree in molecular biology Biochemistry Bioengineering or a related field with a 4 years of experience in lipid nanoparticle research and drug delivery systems OR
Bachelors degree in molecular biology Biochemistry Bioengineering or a related field with a 6 years of experience in lipid nanoparticle research and drug delivery systems
Preferred Qualifications:
PhD degree in Molecular Biology Biochemistry Bioengineering or a related field with a strong background in lipid nanoparticle research and drug delivery systems
Extensive handson experience with molecular biology techniques including nucleic acid manipulation gene expression analysis and cellbased assays.
Proficiency in lipid nanoparticle formulation characterization and analysis techniques. Knowledge in techniques such as DLS zeta potential measurements and TEM would be a plus.
Excellent analytical and problemsolving skills with the ability to design and execute wellcontrolled experiments.
Strong written and verbal communication skills with the ability to present complex scientific data effectively.
Ability to work independently and as part of a collaborative team in a dynamic research environment.
Familiarity with GLP regulatory guidelines and safety protocols.
Research experience in the field of lipid nanoparticlebased drug delivery or related areas.
Experience with in vivo studies and animal models relevant to therapeutic applications.
Knowledge of bioinformatics tools and computational approaches for data analysis.
Familiarity with intellectual property and patent writing.
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Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid longterm durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune systems ability to recognize and tumors. Kite is based in Santa Monica CA. For more information on Kite please visit . Sign up to follow @KitePharma on Twitter at jobs in the United States:
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