Job Summary
The Hans Haecker lab in the Department of Pathology Division of Microbiology & Immunology has an immediate opening for a postdoctoral fellow to study inflammatory signaling pathways TLR IL17Rfamilies) and developing small molecule inhibitors. University of Utah Health was ranked 19th out of 100 top health care institutions worldwide for scientific research by the Nature Index. Haecker Lab has a longstanding interest in Innate Immunity and Signal Transduction. In previous work we identified and characterized various components of the TLR signaling pathways and also developed an innovative drug screening platform to identify small molecules with TLR inhibitory activity using high throughput screening HTS . See Science Signaling 2018 and ChemMedChem 2018 . We are currently extending this HTS approach to other key inflammatory receptors including the IL17R family. The focus of this preclinical drug development project is to utilize HTS to identify small molecule hits for exploration of inflammatory signaling pathways and possible starting point for further drug development.
Responsibilities
The project provides an ideal opportunity for fellows who are interested in (i) innate immunity and inflammation (ii) signal transduction and (iii) drug development. For more information related to the lab the breadth of resources at the University of Utah and the stunning environment of Utah and Salt Lake City please see: Qualifications
Qualifications: Applicants should hold a PhD and/or MD degree in Biochemistry Biology or Immunology.