UNIV - Research Specialist III - Surgery Center for Cellular Therapy
UNIV - Research Specialist III - Surgery Center for Cellular Therapy
Employer Active
Job Alert
You will be updated with latest job alerts via email
Share
Job Alert
You will be updated with latest job alerts via email
$ 46655 - 86321
1 Vacancy
Job Description
Job Description Summary
The Department of Surgery is actively recruiting for a Research Specialist III. The RSIII will perform all investigational cellular product derivation in the Center for Cellular Therapy (CCT) at MUSC. Major duties include perform immunomonitoring and other activities in the CCT; participating training and implementation of procedures implementing new projects that support the growth and business development of the facility with guidance from CCT scientific directors; assist the quality control director with product quality assurance. Together with other team members order and maintain reagents and supplies needed for each CCT projects.Entity
Medical University of South Carolina (MUSC Univ)Worker Type
EmployeeWorker SubType
Research GrantCost Center
CC000957 COM Center For Cellular Therapy CCPay Rate Type
SalaryPay Grade
University06
Pay Range
Scheduled Weekly Hours
40Work Shift
Job Description
Pay Range:
$46655.00 $66488.00 $86321.00 (min mid max)
Job Duties:
25 Research Specialist III who participates in producing standardofcare cellular product derivation is responsible for assay development and implementation of assay protocols. Standard Operating Procedures (SOPs) will be optimized written and validated for ongoing and future products. Participate in the standard of care protocols including performing the Autologous Islet Transplant (AIT) program and the CD34 selection program for SCID patients. Protocols include but are not limited to complex advanced Flow Cytometry operation and maintenance of protocolspecific instruments and documentation of product data. Techniques include tissue dissection tissue purification isolation and preparation of cellular products for reimplantation. Complete product release criteria such as propidium iodide staining for cellular viability endotoxin quantification bacterial contamination testing and mycoplasma detection by luminescence as needed.
25 Work with cultures and various cell types including but not limited to mesenchymal stem cells T cells tumorinfiltrating lymphocytes tumor cells and dendritic cells. Perform experiments investigating cellular and molecular mechanisms involved in immune cell function. Specifically the applicant will be involved in processing the human blood and tissue specimens and isolating PBMCs for immunomonitoring. This will include using FACSbased assays to understand the cell surface expression of various markers that can correlate to the health and age of the lymphoid and myeloid populations. Candidate is also expected to utilize cell and molecular biology techniques including but limited to cell culture molecular cloning and enzymatic assays; transfections and gene expression assays; protein RNA and DNA isolation and separation; ELISA; realtime RTPCR; immunostaining and flow cytometry; proliferation and apoptosis assays and immunohistochemistry.
15 Participate in the bone marrow transplant program. Will work directly with customers to develop products by applying guiding principles and existing frameworks to new contexts.
15 Participate in diagnostic testing programs for research by providing a shared resource to investigators at MUSC external private investigators and industrysponsored investigators. Coordinate the receipt and inventory of research samples plan testing schedule and provide test results data analysis and other requests by the investigator.
10 Help obtain PBMCs from the peripheral blood or leukapheresis samples. Culture lymphoid and myeloid cells for cellular engineering using viral constructs or gene manipulation methodologies.
10 Work closely with the Quality Assurance Director to maintain and assist with IQ/OQ/PQ on all laboratory equipment. Perform maintenance and calibration work when needed.
Additional Job Description
Minimum Requirements:
A bachelors degree in chemistry biology or other natural life or health care science directly related to the assigned area of research and two years advanced journellevel work experience in a clinical or research setting.
Physical Requirements:
(Note: The following descriptions are applicable to this section: Continuous 68 hours per shift; Frequent 26 hours per shift; Infrequent 02 hours per shift) Ability to perform job functions in an upright position. (Frequent) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb using step stool. (Infrequent) Ability to work in temperature extremes 32 F to 100 F) when required due to assignments in cold rooms and/or foreign countries. (Infrequent) Ability to work in confined/cramped spaces. (Continuous) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Frequent) Ability to fully use both legs. (Frequent) Ability to reach in all directions stretch bend while moving items/materials from both sitting and standing positions. (Frequent) Ability to maintain good olfactory sensory function/distinction. (Continuous) Ability to lift materials up to 20 lbs. unassisted. (Infrequent) Ability to lift and carry 4 liter waste material bottles a distance of 30 feet unassisted. (Frequent) Ability to lift and carry 2530 lbs. jugs of liquid a distance of 100 feet unassisted. (Infrequent) Ability to lift file boxes from floor level to counter tops unassisted. (Frequent) Ability to push/ Ability to lift 40 lbs. centrifuge rotors from floor level to height of 40 inches then down 20 inches into centrifuge drum unassisted. (Infrequent) Ability to lift 25 lbs. boxes from floor level to maximum height of 72 inches unassisted. (Infrequent) Ability to push/pull file boxes from one location to another at floor level. (Frequent) Ability to maneuver heavy equipment on bench tops 50 lbs. or greater unassisted. (Frequent) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to maintain 20/40 vision corrected in one eye or with both eyes. (Continuous) Ability to match or discriminate between colors normally. (Continuous) Ability to hear and recognize various alarms emitting from work area systems. (Continuous) Ability to hear and/or understand conversations. (Continuous) Ability to work in a darkroom for processing film etc. (Continuous) Ability to be qualified physically for respirator use initially and annually. (Continuous) Additional New Requirements: Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes tools and equipment as required.
If you like working with energetic enthusiastic individuals you will enjoy your career with us!
The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race color religion or belief age sex national origin gender identity sexual orientation disability protected veteran status family or parental status or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications merit and business need.
Medical University of South Carolina participates in the federal EVerify program to confirm the identity and employment authorization of all newly hired employees. For further information about the EVerify program please click here: Experience:
Unclear Seniority
Employment Type
Full-Time
Key Skills
Similar Jobs
Dr. Job is an online platform that connects employers with skilled job seekers, facilitating the search for job opportunities and top talent. Established in 2015. Dr. Job Pro has emerged as the world premier job portal, attracting thousands of job seekers every day from all over the world.
Follow Dr.Job
Dr Job FZ LLC. 2025 © All Rights Reserved