Senior Scientist Statistical Genetics
Senior Scientist Statistical Genetics
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$ 150000 - 185000
1 Vacancy
Job Description
Variant Bio is a Seattlebased biotechnology company leveraging the power of human genetic diversity to develop lifesaving therapies. To achieve this goal we are studying the genes of people who are outliers for medically relevant traits then translating insights from this research into the discovery and development of new therapeutics.
Variant Bio has raised $130mm to support the rapid advancement of the companys research and development work. Our investors include Lux Capital Alta Partners General Catalyst SoftBank Vision Fund Cercano Management and Casdin Capital among others. Our growing team of geneticists medical researchers biologists and drug hunters is working to advance multiple projects through target validation lead optimization and into the clinic in relentless pursuit of our goal to bring lifesaving therapies to patients.
Ethics is at the foundation of everything we do at Variant Bio. Our genomic research studies are codesigned with local partners around the world. In addition we are committed to sharing tangible benefits with research partners and communities through our unique Benefitsharing Program and Affordable Medicines Pledge.
Variant Bio is an equal opportunity employer that guarantees a work environment that respects and values diversity at our company. We do not discriminate on the basis of race religion color national origin sex gender gender expression sexual orientation age marital status veteran status or disability status.
Job Description
The Genomic Discovery team is seeking a statistical geneticist with expertise in conducting analyses to advance drug discovery. The ideal candidate will have a strong foundation in statistical genetics methods and their applications. The candidate should also have experience applying best practices in statistical genetics and implementing rigorous quality control measures. In this role they will design execute and interpret genetic analyses across diverse populations leveraging insights to drive target identification and validation. We encourage candidates who are passionate about increasing the inclusion of underrepresented populations in genomic research to apply as this is a core mission of Variant Bio. It is strongly preferred that this role is based in Seattle WA and in the office a minimum of 3 days a week.
Responsibilities
- Utilize standard and custom statistical genetics software including tools for genomewide association studies and metaanalyses to conduct analyses.
- Design and implement statistical genetic analyses across a variety of study designs including quantitative traits and family studies.
- Interpret results and refine followup analyses to ensure proper inference and support downstream applications.
- Familiar with postGWAS analysis methods such as colocalization conditional analysis finemapping and mendelian randomization.
- Work with bioinformaticians software engineers and cloud architects to mature workflows and integrate approaches into existing infrastructure.
- Communicate results internally and externally through presentations and publications.
Qualifications
- Ph.D. with 4 years of experience 10 years with Masters in statistical genetics genetic epidemiology or related field.
- Experience using genetics in drug discovery activities.
- Solid conceptual background in the key principles of population and statistical genetics as well as formal training in statistics or genetic epidemiology.
- Good working knowledge of public human genomic resources such as the 1000 Genomes Project the Human Genome Diversity Project gnomAD the UK Biobank and other biobanks.
- Strong programming skills and experience with high performance computing.
- Independent creative detailorientated and a critical thinker.
- Compelled by the companys mission of great science a strong ethical stance and benefit sharing.
What We Offer
- Opportunity to be part of a well funded and highly innovative biotech.
- Competitive industry leading salary and comprehensive benefits including medical dental vision short and long term disability and life insurance.
- 401(k) plan through Fidelity that includes up to 3 employer match and flexible investment options.
- Flexible paid time off.
- Choice of public transportation (Orca Card) provided by the company or subsidized parking.
- Centrally located Eastlake Seattle location in a new Alexandria building with modern facilities.
Anticipated annual base salary for this position is $150000 $185000 plus up to 15 bonus and an options package for total compensation of up to $172500 $212750 plus equity options.
The annual salary range above is based on the responsibilities and qualifications listed above. Individual salary will depend on jobrelated knowledge skills and experience.
Dont meet every single requirement but are excited to join the Variant Bio team If your past experience doesnt align perfectly with every qualification in the job description we encourage you to apply anyway. You may still be the right candidate for this or other roles.
Required Experience:
Senior IC
Employment Type
Full Time
