Senior Scientist II
Senior Scientist II
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Salary Not Disclosed
1 Vacancy
Job Description
AbbVie is searching for a highly motivated individual to fill a Sr. Scientist I position in the Analytical Development group at AbbVie Bioresearch Center in Worcester MA. Analytical Development is responsible for the development qualification and of analytical methods to provide product and process understanding for biological entities from discovery through commercial stages.
The candidate will be part of the Biomolecular Interactions Group within Analytical Development that is mainly focused on method development and implementation of various immunoassays to monitor process impurities and to assess potency of AbbVies Biologics. Some other techniques/methods utilized in the group include 1 surface plasmon resonance using Biacore for assessment of antigen binding and binding of antibody Fc receptors; 2 qPCR to measure levels of residual DNA and mycoplasma and 3 SDSPAGE/immunoblots to assess antibody reagent recognition of host cell proteins .
The successful candidate will contribute to the development and testing of potency and impurity assays and will contribute to the continuous improvement and innovation within the group.
Responsibilities:
- Develop optimize and qualify ELISA methods to examine biomolecular interactions and monitor processrelated impurities
- Address and solve technical problems independently
- Contribute to host cell protein control strategy and risk assessment
- Contribute to structurefunction relationship study to enhance product understanding
- Represent analytical function in CMC group setting and work collaboratively to drive biological program development
- Provide project updates and results to crossfunctional team and management in both oral and written communication
- Conceive and implement innovative ideas evaluate and integrate stateoftheart technology to improve work process and demonstrate a high level of scientific initiative
- Author technical reports support and contribute to regulatory filings
- Organize and document data and results in an electronic lab notebook
- Efficient IT skills (MS office in particular EXCEL other software to support work)
Qualifications :
- BS MS or PhD degree in biological sciences with 10 (BS) 8 (MS) or 0 (PhD) years of relevant experience in academic or biotech/pharmaceutical industry setting or equivalent
- Minimum of 1 year of handson experience with ELISA and other relevant assays required
- Sound scientific understanding of immunoassays
- Demonstrated record of independent thought creativity and scientific accomplishment (e.g. peer reviewed journal publications patents)
- Demonstrated ability to independently design execute and interpret critical experiments to answer scientific questions
- Goal oriented team player with problem solving skills critical thinking ability and excellent communication skills
- Highly motivated and independent with an ability to adapt to changing priorities in a fastpaced environment
- Excellent documentation skills: documents work
- Automation experience (ie Hamilton) and experience with FRET HTRF and 2D gels/westerns a plus
- Experience providing bioassay and gene therapy support a plus
- Understand and adhere to corporate standards regarding code of conduct safety appropriate handling of material.
Additional Information :
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our shortterm incentive programs.
This job is eligible to participate in our longterm incentive programs
Note: No amount of pay is considered to be wages or compensation until such amount is earned vested and determinable. The amount and availability of any bonus commission incentive benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole and absolute discretion unless and until paid and may be modified at the Companys sole and absolute discretion consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives serving our community and embracing diversity and inclusion. It is AbbVies policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race color religion national origin age sex (including pregnancy) physical or mental disability medical condition genetic information gender identity or expression sexual orientation marital status status as a protected veteran or any other legally protected group status.
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No
Employment Type :
Fulltime
Employment Type
Full-time
