Senior Scientist BioDesign BioTherapeutics Discovery Delivery
Senior Scientist BioDesign BioTherapeutics Discovery Delivery
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Job Description
About This Role
The BioDesign BioTherapeutics Discovery & Delivery group at Biogen is seeking a driven and collaborative Senior Scientist focused on advancing nextgeneration therapeutic strategies for targeted delivery to the brain muscle and other tissues. This labbased role will be central to developing and characterizing biologics including antibodies proteins and oligonucleotide conjugates designed for improved tissue penetration and pharmacological activity. The ideal candidate will bring handson experience in molecular characterization in vivo pharmacology and histological analysis. The successful candidate will contribute to both exploratory platform efforts and portfolio programs playing a key role in generating and characterizing biologic therapeutics experimental method development and close crossfunctional collaboration.
What Youll Do
- Drive the generation and characterization of nextgeneration therapeutic molecules including antibodies proteins and oligonucleotide conjugates by applying a broad range of molecular and biochemical techniques to support both discovery efforts and platform advancement.
- Answer critical biological questions by strategically designing and overseeing complex studies to evaluate therapeutic delivery and pharmacodynamic outcomes in key tissues such as brain and muscle directly shaping experimental direction and translational strategy.
- Analyze pharmacology and tissue biodistribution data to guide candidate prioritization refine targeting approaches and influence scientific direction across diverse therapeutic modalities.
- Combine handson expertise in bioanalytical methods (e.g. MSD ELISA IHC) with highlevel coordination of platform initiatives building sustainable capabilities in tissueenhanced delivery.
- Drive the continued evolution of the tissue enhanced delivery platform through innovation in receptor targeting molecular design and delivery strategies that expand therapeutic access to challenging tissues.
- Communicate scientific findings effectively across interdisciplinary teams contributing to internal reports protocols and strategic discussions that guide platform and pipeline advancement.
Who You Are
You are an experienced bench scientist with a strong background in in vivo pharmacology and tissuelevel analysis. You are comfortable designing experiments working with crossfunctional teams and contributing to translational research efforts. You are detailoriented resourceful and energized by applying science to solve complex delivery challenges.
Qualifications :
Required Skills
- Ph.D. in biochemistry chemical biology or a related field with 25 years experience or a Masters degree with 68 years relevant industry experience.
- Demonstrated expertise in antibody engineering principles and standard protein characterization techniques (eg. kinetics stability epitope binning) particularly in tissue specific delivery to the brain and muscle.
- Proficiency in animal study design biologics dosing and tissue analysis methods including tissue processing MSD IHC and image acquisition/quantification.
- Demonstrated ability to independently design plan execute and interpret complex experiments.
- Strong organizational and communication skills with the ability to work independently and in teams. Capable of managing experimental timelines and collaborating across functions
Preferred Skills
- Familiarity with CNS or peripheral tissue delivery strategies including use of shuttle antibodies or receptormediated transport ideally in the context of animal models.
- Experience with complex biologics including bispecific antibodies fusion proteins or engineered scaffolds designed for enhanced tissue targeting and uptake.
- Experience coordinating studies across internal and external teams or CROs.
Additional Information :
The base salary range for this position is $122000 $163000. Base salary offered is determined though an analytical approach utilizing a combination of factors including but not limited to relevant skills & experience job location and internal equity. Regular employees are eligible to receive both short term and longterm incentives including cash bonus and equity incentive opportunities designed to reward recent achievements and recognize your future potential based on individual business unit and company performance.
In addition to compensation Biogen offers a full and highly competitive range of benefits designed to support our employees and their families physical financial emotional and social wellbeing; including but not limited to:
- Medical Dental Vision & Life insurances
- Fitness & Wellness programs including a fitness reimbursement
- Short and LongTerm Disability insurance
- A minimum of 15 days of paid vacation and an additional endofyear shutdown time off (Dec 26Dec 31
- Up to 12 company paid holidays 3 days off for Personal Significance
- 80 hours of sick time per calendar year
- Paid Maternity and Parental Leave benefit
- 401(k) program participation with company matched contributions
- Employee stock purchase plan
- Tuition reimbursement of up to $10000 per calendar year
- Employee Resource Groups participation
Why Biogen
We are a global team with a commitment to excellence and a pioneering spirit. As a midsized biotechnology company we provide the stability and resources of a wellestablished business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning growth and expanding their skills. Above all we work together to deliver lifechanging medicines with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.
At Biogen we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds cultures and perspectives make us a stronger and more innovative company and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about our DE&I efforts.
All qualified applicants will receive consideration for employment without regard to sex gender identity or expression sexual orientation marital status race color national origin ancestry ethnicity religion age veteran status disability genetic information or any other basis protected by federal state or local law. Biogen is an EVerify Employer in the United States.
Remote Work :
No
Employment Type :
Fulltime
Employment Type
Full-time
