Process Development Senior Scientist

Career Category

Job Description

Join Amgens Mission of Serving Patients

At Amgen if you feel like youre part of something bigger its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980 weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology Inflammation General Medicine and Rare Disease we reach millions of patients each year. As a member of the Amgen team youll help make a lasting impact on the lives of patients as we research manufacture and deliver innovative medicines to help people live longer fuller happier lives.

Our awardwinning culture is collaborative innovative and science based. If you have a passion for challenges and the opportunities that lay within them youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Process Development Senior Scientist

What you will do

Lets do this. Lets change the world. In this vital role you will be responsible for the invention development characterization and implementation of synthetic drug substance manufacturing processes and technologies to advance Amgens exciting small molecule and hybrid portfolio. The Senior Scientist role will include supporting the development of efficient and sustainable manufacturing processes to prepare peptides oligonucleotides and/or antibody drug conjugates driving technology innovation to support bioconjugation and providing technical expertise towards manufacturing and commercialization.

Responsibilities:

• Work with a diverse team of synthetic chemists chemical engineers and analytical chemists to develop sustainable and costeffective processes for synthetic peptide oligonucleotide and/or antibody drug conjugate manufacturing
• Drive technology innovation in the synthesis purification and characterization of bioconjugates
• Support cGMP manufacturing and technology transfer to largescale production facilities
• Develop strategies to ensure process performance through process understanding modeling and characterization
• Guide successful completion of project deliverables and ensure timelines are met
• Work crossfunctionally to deliver regulatory documents and support regulatory filings
• Serve as a technical expert and keep current in the field of peptide oligonucleotide and antibody drug conjugate manufacturing
• Coach and provide career and scientific / technical advice to colleagues within the organization
• Interface with Research / Discovery teams to advance programs into Process Development and towards clinical development milestones.

What we expect of you

We are all different yet we all use our unique contributions to serve patients. The professional we seek is a scientist with these qualifications.

Basic Qualifications:

Doctorate degree PhD OR PharmD OR MD and relevant postdoc where applicable

Or

Masters degree and 3 years of Chemistry Biochemistry or Chemical Biology experience

Or

Bachelors degree and 5 years of Chemistry Biochemistry or Chemical Biology experience

Preferred Qualifications:

• Extensive handson expertise in the synthesis and purification of peptides oligonucleotides and/or antibody drug conjugates and experience with bioconjugation techniques
• Proficiency in analytical characterization techniques such as Hydrophobic Interaction Chromatography (HIC)HPLC Size Exclusion Chromatography (SEC) Liquid ChromatographyMass Spectrometry (LCMS) IonExchange (IEX) and Reversed Phase (RP)HPLC.
• Demonstrated ability to work within a dynamic and interdisciplinary environment to achieve results
• Peoplecentered leadership skills in building strong teams through mutual trust and respect and exhibits Amgen leadership attributes of inspire accelerate integrate and adapt
• Proven track record of publications patents and presentations

What you can expect from us

As we work to develop treatments that take care of others we also work to care for your professional and personal growth and wellbeing. From our competitive benefits to our collaborative culture well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to relevant skills experience and qualifications.

In addition to the base salary Amgen offers a Total Rewards Plan based on eligibility comprising of health and welfare plans for staff and eligible dependents financial plans with opportunities to save towards retirement or other goals work/life balance and career development opportunities that may include:

• A comprehensive employee benefits package including a Retirement and Savings Plan with generous company contributions group medical dental and vision coverage life and disability insurance and flexible spending accounts
• A discretionary annual bonus program or for field sales representatives a salesbased incentive plan
• Stockbased longterm incentives
• Awardwinning timeoff plans
• Flexible work models including remote and hybrid work arrangements where possible

Apply now and make a lasting impact with the Amgen team.

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Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

As an organization dedicated to improving the quality of life for people around the world Amgen fosters an inclusive environment of diverse ethical committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race color religion sex sexual orientation gender identity national origin protected veteran status disability status or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process to perform essential job functions and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race color religion sex sexual orientation gender identity national origin protected veteran status or disability status.

Salary Range