Senior Scientist - Organic Chemistry Bioconjugation
Senior Scientist - Organic Chemistry Bioconjugation
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1 Vacancy
Job Description
Who We Are:
At Veranova we believe people are our most important asset and we are dedicated to building the most talented and diverse workforce in our industry. Our commitment to uncompromising focus on quality compliance safety and excellence in delivery shapes everything we do. We are not just looking for skills; we are seeking innovative individuals who have a mindset open to learning and growth and a desire to make a difference.
Veranova is a global leader in the development and manufacturing of complex active pharmaceutical ingredients (APIs) for pharma and biotech customers. With deep technical expertise and impressive flexibility we develop solutions and processes that support and accelerate innovation.
Join us on our mission to enable current and nextgeneration therapeutics to improve and save the lives of patients.
Role Overview:
We are seeking a highly motivated and skilled organic chemist with bioconjugation experience to join our team in New England. The successful candidate will be an experienced process development scientist also experienced in performing bioconjugations in a research and development setting. The individual will play a key role in the implementation of bioconjugation capabilities in a clinical API facility to produce antibody drug conjugates and other complex bioconjugates. This position offers an exciting opportunity to contribute to the advancement of cutting edge biotherapeutics in a fastpaced collaborative environment.
Core Responsibilities:
- Develop and implement phase appropriate bioconjugation development strategies for the attachment of cytotoxic payloads peptides oligonucleotides or other small molecules to antibodies proteins peptides or other therapeutic entities.
- Design and implement methods to enable the synthesis purification isolation and scale up of any chemical transformations from small molecules ADC peptides and bioconjugation entities.
- In depth safety understanding and handling of bioconjugation manufacturing process Synthesis Purification Isolation and Characterization.
- Work closely with other scientists and engineers to scaleup and transfer bioconjugation processes from bench to cGMP manufacturing.
- Troubleshoot and resolve issues related to bioconjugation including yield optimization purity and stability of final products.
- Perform comprehensive analysis of bioconjugates using techniques such as HPLC mass spectrometry SDSPAGE SEC and UVVis spectrophotometry.
- Quantify drugtoantibody ratio (DAR) assess conjugate stability and characterize impurities.
- Collaborate with manufacturing teams to ensure smooth technology transfer from laboratory to pilot scale and fullscale production.
- Provide support for cGMP manufacturing campaigns ensuring compliance with regulatory requirements and documentation standards.
- Assist in troubleshooting manufacturing issues and process optimization to improve product yields and quality.
- Work closely with process engineers quality control analytical development and regulatory affairs teams to ensure successful project delivery.
- Communicate technical findings and results to both internal and external stakeholders including clients and regulatory bodies.
- Prepare and maintain detailed documentation of experimental procedures results and data analysis in compliance with GMP GLP and internal quality standards.
- Support regulatory submissions by providing technical input data packages and scientific justifications.
Qualifications:
- Ph.D. in organic chemistry or related field with 2 years of postdoctoral or industry experience including handson experience in bioconjugation
- M.S. in organic chemistry or related field with 4 years of industry experience including handson experience in performing bioconjugation
- Strong knowledge of bioconjugation techniques (e.g. sitespecific conjugation linker chemistry ADC development).
- Experience with analytical techniques such as mass spectrometry HPLC and protein characterization.
- Ability to design and execute experiments analyze complex data and troubleshoot bioconjugation challenges.
- Strong communication and teamwork skills in a crossfunctional environment.
Our Commitment:
Health & Wellness: Comprehensive health & Wellness benefits. Access to mental health resources and wellness programs. Generous PTO and holiday pay policies.
Financial Wellness: Comprehensive total compensation package that includes competitive base salary Defined Contribution Pension program eligibility for performancebased bonuses and attractive 401(k) Plan with company match.
Professional Development: Opportunities for continuous learning through LinkedIn Learning workshops conferences and mentorship. Tuition Assistance for Undergraduate and Graduate degree programs.
Inclusive Culture: At Veranova an inclusive culture is integral to our values. We are committed to ensuring that everyone can bring their full self to work and thrive in their career.
How to Apply:
At Veranova we are on a misson to meet people that believe in our values and can contribute to the team in a variety of ways. Please visit www.veranova to view all open roles and join our Talent Community to stay connected and learn about opportunities as they arise.
We value a range of experiences and perspectives. If you want to be part of improving and saving the lives of patients we encourage you to apply regardless of whether you meet every qualification listed.
If you are a veteran first responder or in the process of transitioning from service member to civilian life we encourage you to apply. Your experience brings invaluable skills and insights that can contribute to our team.
For applicants who may require a reasonable accommodation for any part of the application or hiring process due to a disability you may submit your request by sending an email to in order to confirm your request for an accommodation. Please include the job number title and location of role. This option is reserved for individuals who require accommodation due to a disability. Information received will be processed by a U.S. Veranova employee and then routed to a local recruiter who will provide assistance to ensure appropriate consideration in the application or hiring process.
Additional Information:
Applicants for this role must be authorized to work in the United States without further employer sponsorship.
Agency and Search Firm Representatives: Veranova does not accept unsolicited resumes from agencies and/or search firms for this job posting.
Important Notice Regarding Recruitment Scams: Veranova is committed to providing a professional and secure recruitment experience for all applicants. Unfortunately fraudulent job postings and recruitment scams are becoming more prevalent. We want to ensure that all candidates are aware of potential scams. Please see our notice here.
- Legitimate communications from Veranova will only come from official email addresses using our domain: @veranova.
- Legitimate LinkedIn communications will only come from active Veranova employees.
- Veranova will never ask candidates for sensitive personal information during the application process (e.g. bank account details or social security number).
- Veranova will never ask candidates for payment (e.g. for equipment training or background checks).
If you have any doubts or concerns about the authenticity of a job posting please reach out to our HR department: (US) or (UK).
All your information will be kept confidential according to EEO guidelines.
Veranova is an Equal Opportunity Employer. It is the policy of Veranova to provide equal employment access and opportunity to all persons regardless of age race color national origin religion sex sexual orientation gender identity and/or expression physical or mental disability genetic information citizenship marital status veteran status or any other characteristic protected by federal state or local law.
All applications are carefully considered and your details will be stored on our secure Application Management System. This is used throughout Veranova for the selection of suitable candidates for our vacancies as they arise. Veranova respects your privacy and is committed to protecting your personal information. For more information about how your personal data is used please view our privacy notice.
Required Experience:
Senior IC
Employment Type
Full-Time
