Research Lab Tech I Miyamotos Lab - Radiation Oncology

Site: The General Hospital Corporation

At Mass General Brigham we know it takes a surprising range of talented professionals to advance our missionfrom doctors nurses business people and tech experts to dedicated researchers and systems analysts. As a notforprofit organization Mass General Brigham is committed to supporting patient care research teaching and service to the community. We place great value on being a diverse equitable and inclusive organization as we aim to reflect the diversity of the patients we serve.

At Mass General Brigham we believe a diverse set of backgrounds and lived experiences makes us stronger by challenging our assumptions with new perspectives that can drive revolutionary discoveries in medical innovations in research and patient care. Therefore we invite and welcome applicants from traditionally underrepresented groups in healthcare people of color people with disabilities LGBTQ community and/or gender expansive first and secondgeneration immigrants veterans and people from different socioeconomic backgrounds to apply.

Job Summary

Reporting to the Principal Investigator the Research Technician I in the Department of Radiation Oncology at Massachusetts General Hospital (MGH) works as part of a multidisciplinary team and will be responsible for a range of activities detailed below.

The incumbent works as part of a multidisciplinary team and will be responsible for a range of activities including but not limited to:

• Isolation and analysis of circulating tumor cells (CTCs) from patient blood samples using microfluidic technologies.
• Molecular analysis of CTCs tumors and normal tissue samples using molecular biology and cellular biology techniques including RNA in situ hybridization qPCR droplet digital PCR immunofluorescence flow cytometry and nextgeneration sequencing.
• Perform standard molecular biology techniques including nucleic acid purification PCR cloning sitedirected mutagenesis and plasmid construction.
• Perform standard tissue culture and cell biology techniques including cell line maintenance drug treatments plasmid transfection Western blotting cell viability assays and immunofluorescence microscopy.
• Perform bioinformatic analyses including differential gene expression profiling and genomic mutational landscape analysis of tumors.
• Order common laboratory reagents and general laboratory supplies.
• Participate in upkeep of the lab and basic maintenance of laboratory equipment.
• Organize and accurately maintain written records of experimental procedures and data collection.
• Participate in weekly lab meetings.
• Assist in preparation of manuscripts resulting from data generated in research projects.

• Able to work independently and as part of a team
• Excellent verbal and written communication skills
• Laboratory research techniques (training will be provided)
• Attention to details in experimental techniques and record keeping
• Facility with computer software for data analysis
• Excellent organizational skills working well under pressure
• Multitasking

Onsite

149 Thirteenth Street Building 149

40

Regular

Day (United States of America)

The General Hospital Corporation is an Affirmative Action Employer. By embracing diverse skills perspectives and ideas we choose to lead. All qualified applicants will receive consideration for employment without regard to race color religious creed national origin sex age gender identity disability sexual orientation military service genetic information and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process to perform essential job functions and to receive other benefits and privileges of employment.

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