Vector DesignProtein Design Scientist
Vector DesignProtein Design Scientist
Posted on :
10-04-2025
Employer Active
1 Vacancy
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Monthly Salary
Not Disclosed
Salary Not Disclosed
Vacancy
1 Vacancy
Posted on :
10-04-2025
Job Description
Help us create a brighter tomorrow with biology. Were looking for missiondriven talented and kind people to join our team.
About this Job
Were looking for a Senior Scientist with deep experience in cell line development for pharmaceutical protein production. This role will be part of the synthetic biology team and will work closely with members from the optogenetics bioprocess development and analytical chemistry teams to revolutionize biomanufacturing.
Responsibilities
- Design build and test vectors to bring two high value protein targets through conventional cell line development within 9 months
- Contribute to the design build and testing of vectors for optogenetic cell line development
- Codify Prolifics engineering principles as it relates to the production of secreted proteins
- Build and refine a company wide vector construction platform for standard and difficult to produce proteins
- Close collaboration with commercial and product managers to identify requirements for prospective targets
- Close collaboration with synthetic biology and optogenetic teams to ensure learnings are translated across research groups for R&D and commercial purposes
- Analysis documentation and presentation of experimental data across teams and to leadership
- Contribute to expanding the intellectual property (IP) portfolio
- Contribute to a comprehensive FTO strategy for cell line engineering
About You
- Extensive individual contributor experience in the vector/protein design/cell line engineering field with a track record of bringing targets through discovery and scale up
- Experience designing expression constructs with optimal signal peptides linkers and tags for improved yield and purification
- Experience applying sequence optimization strategies (e.g. codon optimization surface charge engineering) to enhance production.
- Experience using structureguided protein tools (e.g. Rosetta AlphaFold PyMOL) to inform rational protein design modifications that consider stability secretion and functionality is a plus.
- PhD in bio/chemical engineering biotechnology biochemistry or another relevant discipline or equivalent experience
- Experience with highthroughput cell line development environments using automation
- Enjoy both leading and carrying out independent projects and experimental work
- Excited about working with interdisciplinary teams
- Have strong communication skills and comfortable teaching and sharing knowledge at multiple levels of technical detail
- Eager to work in a highgrowth fastpaced and dynamic startup environment
- Comfortable pushing the boundaries of what is known to create innovative solutions
$130000 $195000 a year
Note we are considering multiple job levels within this range.
Diversity:We value diverse people perspectives and knowledge. To this end we aim to foster a sense of belonging that enables everyone to bring their whole authentic self to work everyday. We are committed to growing a diverse and inclusive team that encompasses all types of people. We believe this can only be achieved by acknowledging the ancestral historic and current systemic and communal inequities.
Location:The San Francisco Bay Area (Emeryville CA)
Benefits:Companycovered medical dental and vision insurance for employee and spouse generous equity package retirement plan with company contribution flexible PTO with healthy time off minimums career coaching and mental health support and plentiful snacks and free lunch every day!
Employment Type
Full-Time
Key Skills
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