Senior Scientist - Nuclear Magnetic Resonance
Senior Scientist - Nuclear Magnetic Resonance
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$ 104000 - 186160
1 Vacancy
Job Description
We are looking for experienced Nuclear Magnetic Resonance (NMR) spectroscopist to aid in these efforts. The candidate will work in an exciting fastpaced research environment as the candidate studies large and dynamic protein kinases by NMR spectroscopy. The unparalleled NMR center at St. Jude includes three 600 MHz two 700 MHz four 800 MHz 850 MHz and the first 1.1 GHz in the world. The research activity will be supported by Blue Sky initiative. This role will involve working closely as part of a multidisciplinary team including biochemists structural biologists computational chemists and other biophysical specialists.
St. Jude offers a remarkable opportunity to perform cutting edge research with outstanding institutional support and exceptional shared core facilities in an environment of open collaboration educational advancement and training opportunities. St. Jude is consistently ranked on Fortune Magazines and Glassdoors 100 Best Places to Work for companies with 1000 or more employees. We are located in the heart of Memphis Tennessee a vibrant and friendly city at the historic American crossroads of music trade food and culture. Mild winters and beautiful green outdoor spaces are part of the reasons why Forbes recently named Memphis the 4th happiest city in which to work. Cost of living and high quality of life are other attractions: Money magazine listed Memphis as one of the least expensive cities in which to raise a child. St. Jude facilities and salaries are highly competitive.
Key Responsibilities:
- Conduct experiments/projects independently under the overall direction of supervisor. Including construct design chemical shift assignment structure determination and dynamics studies.
- Critically evaluate viability of kinase for dynamics and/or structural studies.
- Analysis of CEST relaxation profiles.
- Structure calculations using CYANA.
- Work closely with biochemist to produce samples.
- Train and oversee the work of others in NMR techniques and procedures associated with chemical shift assignment structure determination and dynamics studies.
- Independently troubleshoot solve difficult problems and propose solutions related to research project design and .
- Work effectively in a collaborative team environment where results are achieved through influence cooperation and the incorporation of multiple points of view.
Ideal Candidate:
- Extensive experience in applying NMR techniques in characterization of the structure and dynamics of large proteins including backbone and methyl assignment methodologies.
- Experience in using both automated and manual methods for assignment of both backbone and methyl groups.
- Experience in performing characterization of protein dynamics using CEST.
- Proficient in data processing using NMRPipe.
- Experienced in NMR structure calculation and refinement.
- Independently motivated detail oriented and good problemsolving ability.
- Excellent organizational skills with an ability to embrace change and multitask in an extremely fastpaced environment.
- Excellent communications skills.
Additional preferred skills:
- Proficiency in using nmrfam Sparky Bruker TopSpin and CYANA.
- Experience using MAGIC algorithm for automated methyl assignments of methyl.
Minimum Education/or Training:
- Bachelors degree in relevant scientific area is required.
- PhD in NMR spectroscopypreferred.
Minimum Experience:
- Ten 10 years relevant work experience is required with a Bachelors degree.
- Eight 8 years of relevant work experience is required with a Masters degree.
- Five 5 years of relevant work experience is required with a PhD.
Have More in Memphis
Get the best of bigcity amenities mixed with all the charm of a smalltown feel when you live in Memphis. From our worldrenowned music scene to our eclectic mix of food and people. Memphis is a place our employees are proud to call home. Our region enjoys a cost of living more than 20 lower than the national average and our state places no personal income tax on wages. Plus Memphians spend five hours less per year in their daily commute compared to the national average. Learn how you can Have More in Memphis.
Compensation
In recognition of certain U.S. state and municipal pay transparency laws St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets experience and training licensure and certifications and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $104000 $186160 per year for the role of Senior Scientist Nuclear Magnetic Resonance.Explore our exceptional benefits!
No Search Firms
St. Jude Childrens Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.
Required Experience:
Senior IC
Employment Type
Full-Time
