Research Position in Computational GenomicsPositions are available for computational biologists or bioinformatic specialists in the Talkowski laboratory in the Center for Human Genetic Research at Massachusetts General Hospital and Harvard Medical School as well as the Program in Medical and Population Genetics at the Broad Institute. Projects involve characterization of genomic variation and functional genomic studies of neurodevelopmental disorders particularly autism spectrum disorder (ASD).Candidates will have the opportunity to work in a unique translational genomics environment that will integrate computational genomics technology development and an advanced molecular genomics laboratory. Candidates will focus on genomic variation from wholegenome sequencing particularly structural variation or projects related to integration of functional genomics datasets in the characterization of the consequences of strong effect mutations in ASD in human pluripotent stem cells and their derivatives. Candidates will have significant independence with appointments to MGH HMS and the Broad Institute and will interact with collaborators at all three institutions. The ideal candidate will have an interdisciplinary background in bioinformatics & computational biology advanced expertise in the analysis and interpretation of nextgeneration sequencing data focusing (DNA sequencing RNAseq ChIPseq) and its integration with other omics data or demonstrated expertise in human genetics and bioinformatics; good programming skills; and advanced knowledge of statistical methods.Required Skills A Ph.D. in human genetics quantitative genetics computational biology bioinformatics computer science and statistics or mathematics is strongly preferred although a truly exceptional candidate with a Masters degree or Bachelors degree in these fields may be considered. Ability to program in Python Perl and R. Expertise with Unix systems and parallel computing. Familiarity with genomics analysis tools. Excellent communication skills both written and oral. All candidates should provide a cover letter and academic curriculum vitae or resume and if selected for an interview will be required to provide three letters of reference from academic or industry supervisors.Massachusetts General Hospital is an Equal Opportunity Employer. By embracing diverse skills perspectives and ideas we choose to lead. Applications fromprotected veterans and individuals with disabilities are strongly encouraged.
Required Experience:
Unclear Seniority
Bioinformatics Specialist I
