Technical Research Assistant II Laboratory for Translational Research on Neurodegeneration
Technical Research Assistant II Laboratory for Translational Research on Neurodegeneration
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Job Description
At Mass General Brigham we know it takes a surprising range of talented professionals to advance our missionfrom doctors nurses business people and tech experts to dedicated researchers and systems analysts. As a notforprofit organization Mass General Brigham is committed to supporting patient care research teaching and service to the community. We place great value on being a diverse equitable and inclusive organization as we aim to reflect the diversity of the patients we serve.
At Mass General Brigham we believe a diverse set of backgrounds and lived experiences makes us stronger by challenging our assumptions with new perspectives that can drive revolutionary discoveries in medical innovations in research and patient care. Therefore we invite and welcome applicants from traditionally underrepresented groups in healthcare people of color people with disabilities LGBTQ community and/or gender expansive first and secondgeneration immigrants veterans and people from different socioeconomic backgrounds to apply.
Job Summary
McLean Hospital is a comprehensive psychiatric hospital committed to providing easy access to superior quality costeffective mental health services in the Boston area Massachusetts and beyond. Since 1811 McLean Hospital has been a world leader in the treatment of mental illness and chemical dependency research into the cause of mental illness and the training of generations of mental health care providers. McLeans multidisciplinary programs treat a broad range of psychiatric illnesses across the full continuum of care.We are looking for an RA to help us in our studies of the role of bioenergetics in Alzheimers disease (AD). Our work is focused on understanding the molecular and cellular mechanisms in AD and particularly how changes in metabolic and bioenergetic cell functions during the aging process contribute to the pathogenesis of AD. We work with fibroblast cell lines and induced pluripotent stem cells (iPSC) that are derived from AD patients and healthy control individuals. The fibroblasts and neural cell populations differentiated from the iPSC lines are analyzed for their molecular and cellular phenotypes and functions with an emphasis on metabolism and bioenergetics.
Working under the general supervision of a Senior Technical Research Assistant Manager or Principal Investigator with assistance of summer interns and junior staff and following established policies and procedures the RA will conduct a variety of routine experiments where methodologies are clearly established. They may also calculate transcribe and analyze data using basic statistics and may perform literature searches under direction.
PRINCIPAL DUTIES ANDRESPONSIBILITIES: Under general supervision performs routine experiments which can be moderate to complex. Experiments may include tissue culture preparing special materials performing molecular biology and biochemical assays immunocytochemistry and fluorescent microscopy imaging and computational data analysis.
Maintains longterm tissue cultures of human cell lines and monitors cells for viability and contamination differentiation of stem cells and geneengineering using lentivirus vector technologies.
Record data summarizes and analyzes results using basic statistics.
Prepares laboratory reagents and chemicals. Maintains instruments and equipment.
Maintains supplies inventory in accordance with departmental procedures.
Discusses progress of work regularly with supervisor.
Performs all other duties as assigned.
All McLean team members are expected to consistently demonstrate our values of integrity compassion respect diversity teamwork excellence and innovation in their work activities and interactions.
Qualifications
SKILLS/ABILITIES/COMPETENCIES REQUIRED:
Basic techniques in cell culture molecular and cellular biology and biochemistry general lab work and the of complex experimental designs.
High degree of computer literacy.
Good interpersonal and communication skills.
Good organizational skills detail oriented.
Ability to methodically record data and to analyze data using basic statistics.
Ability to perform a variety of routine tests and prioritize work.
Ability to demonstrate professionalism.
Successful candidate must possess basic computer skills in order to use a variety of electronic systems to access and/ormaintainpersonal employmentrelated data satisfy required annual trainings and use jobspecific applications. All employees of McLean Hospital are assigned an email account for business communication purposes. Candidate must also be able to consistently demonstrate McLean Values of integrity compassion and respect diversity and teamwork excellence and innovation in their work activities and interactions.
Qualifications
1. BS or BA in a biological/physical science required.
2. Some relevant work experience
3. Sound independent judgment and competence in research methodologies.
For RA level II at least one year experience post degree required
Additional Job Details (if applicable)
Remote Type
Work Location
Scheduled Weekly Hours
Employee Type
Work Shift
EEO Statement:
Mass General Brigham Competency Framework
At Mass General Brigham our competency framework defines what effective leadership looks like by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half PeopleFocused half PerformanceFocused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance make hiring decisions identify development needs mobilize employees across our system and establish a strong talent pipeline.
Employment Type
Full-Time
