Research Assistant I NEUROLOGY RESEARCH SM
Research Assistant I NEUROLOGY RESEARCH SM
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Job Description
At Mass General Brigham we know it takes a surprising range of talented professionals to advance our missionfrom doctors nurses business people and tech experts to dedicated researchers and systems analysts. As a notforprofit organization Mass General Brigham is committed to supporting patient care research teaching and service to the community. We place great value on being a diverse equitable and inclusive organization as we aim to reflect the diversity of the patients we serve.
At Mass General Brigham we believe a diverse set of backgrounds and lived experiences makes us stronger by challenging our assumptions with new perspectives that can drive revolutionary discoveries in medical innovations in research and patient care. Therefore we invite and welcome applicants from traditionally underrepresented groups in healthcare people of color people with disabilities LGBTQ community and/or gender expansive first and secondgeneration immigrants veterans and people from different socioeconomic backgrounds to apply.
Job Summary
We are seeking a talented Research Assistant with experience in neuroscience computer science and network science. The Research Assistant will join the Synaptic and Network Development (SAND) group an exciting interdisciplinary collaboration at the intersection of neurophysiology human stem cell biology and network science. We will address how genetic changes in autism and related neurodevelopmental disorders (NDD) including Rett syndrome lead to altered neural networks and seizures during early development. Using a novel preparation of human cerebral organoids (Giandomenico et al. 2019 Nature Neuroscience) we now have the ability to understand how brain network function is altered at the cellular scale in NDD human in vitro models. This organoid platform will also be used to test novel therapeutic strategies. We will also develop new computational tools for modulating and analyzing evoked network activity.Summary: Provides assistance to the Principal Investigator and Study Team in coordinating research activities that may include conducting a variety of routine experiments with established methodologies data collection and management and other research activities as assigned.
Does this position require Patient Care No
Essential Functions:
Responsible for data collection management manipulation analysis and reporting.
Study cohort management.
Outreach communication with subjects conducting mailings followup on mailings and obtaining necessary documents.
Provides assistance on work related to epidemiological studies and other populationbased research.
Qualifications
Education:
- Bachelors Degree Science required (Neuroscience or Computer Science preferred)
Experience:
- New grad with some relevant coursework 01 year preferred
- Coding skills in MATLAB and Python preferred
- Ability to work effectively and collaboratively with other group members
Knowledge Skills and Abilities:
- Good interpersonal and communication skills.
- Careful attention to detail.
- Excellent organizational skills and ability to prioritize a variety of tasks.
- Computer literacy including database tool.
- Ability to follow directions and exhibit professionalism.
Key Responsibilities:
- Work closely with experts in human stem cell to create autism and related neurodevelopmental disorders (NDD) disease models in human cerebral organoids from patientderived iPSC lines.
- Perform multielectrode array (MEA) recordings and analyze network activity in the NDD and control human cerebral organoids.
- Work closely with team members in our interdisciplinary collaborations on the development and application of methods for human organoids network recordings and network analysis.
- Apply and develop computational methods for analyzing and modulating spontaneous and evoked activity from MEA recordings and/or calcium imaging.
- Ensure validity and reliability of all data collected and analyzed.
- Keep excellent records of experiments undertake thorough data analysis and make active contributions to the laboratory research environment.
- Write regular internal reports as agreed and draft and/or contribute to reports for submission to research sponsors.
- Prepare and present findings at internal group meetings.
- Draft publications and/or presentations for scientific journals/conferences.
- Contribute to research grant applications.
- Provide guidance to staff and students including training to students and/or other trainees.
- Be an active team member and set positive examples for other team members.
- Contribute and lead administrative tasks related to research and teaching goals.
- Maintain a safe workplace and follow all lab and hospital practices and procedures.
- Any other duties commensurate with the post as directed by the PIs.
Interpersonal & Communication Skills:
- Excellent written and verbal communication skills for working collaboratively including communicating progress and challenges to PIs.
- Rigorous scientific skills for acquiring analyzing and presenting data.
- Excellent time and project management skills.
- Meticulous record keeping for both experimental procedures and for analysis.
- Willingness to adjust working hours in accordance with experimental demands and as necessary for project goals.
- Generosity of spirit and willingness to share and help develop skills in others.
Additional Job Details (if applicable)
Length of appointment:
- One year in the first instance with potential to extend up to one or more years if satisfactory progress is made.
Probation period:
- 90 days
Remote Type
Work Location
Scheduled Weekly Hours
Employee Type
Work Shift
EEO Statement:
Mass General Brigham Competency Framework
At Mass General Brigham our competency framework defines what effective leadership looks like by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half PeopleFocused half PerformanceFocused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance make hiring decisions identify development needs mobilize employees across our system and establish a strong talent pipeline.
Employment Type
Full-Time
