drjobs Associate Director Computational Biology Machine Learning

Associate Director Computational Biology Machine Learning

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1 Vacancy
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Job Location drjobs

Palo Alto, CA - USA

Monthly Salary drjobs

Not Disclosed

drjobs

Salary Not Disclosed

Vacancy

1 Vacancy

Job Description

About Us

DELFI Diagnostics Inc. (DELFI Diagnostics) is developing nextgeneration bloodbased tests that are reliable accessible and deliver a new way to help detect cancer. Employing advanced machinelearning methods to wholegenome sequencing data the DELFI (DNA EvaLuation of Fragments for early Interception) platform is built to address the highestburden health challenges. DELFI Diagnostics prioritizes solutions that have the potential to save lives on a global scale including for historically underserved populations. DELFI Diagnostics platform relies on fragmentomics the discovery that cancer cells are more chaotic than normal cells and when they die leave behind telltale patterns and characteristics of cellfree DNA (cfDNA) fragments. FirstLook Lung for individuals eligible for lung cancer screening is DELFI Diagnostics first laboratorydeveloped screening test and can be part of routine blood work. FirstLook Lung uses millions of data points to reliably identify individuals who may have cancer detected through lowdose CT including early stage disease with a negative predictive value of 99.8 percent. This test has not been cleared or approved by the FDA.

In our passionate pursuit to radically improve health outcomes we serve humanity when we:

Lead with Science Anchor in Pragmatism: We pioneer lifechanging science by ensuring quality transparency and rigor at all times. We explore thoughtfully experiment smartly and deliver impact with conviction.

Build With & For All: We embrace diverse backgrounds to innovate and achieve together. We are not just building a product we aim to disrupt the path of cancer for all no matter geography or socioeconomic class

Put We over I: We are a home for highperforming people. Through teamwork we build collective intelligence. Each of us wins when those we serve and those who serve with uswin. We show up with empathy humility and integrity at every step of the journey.

DELFI has 12 designated inoffice working days each week for employees who live within within 50 miles of Palo Alto CA or Baltimore MD offices

This role is responsible for leading a technical team focused on developing and validating computational algorithms for cancer detection using bloodbased omics data. You will lead crossfunctional collaboration with assay development teams clinical data scientists and software engineers to successfully transition cuttingedge research models into production environments. This position requires a unique blend of technical leadership scientific expertise and collaborative skills to advance cancer detection technologies from research concepts to practical applications.

What youll do

    • Manage and lead a team of data scientists developing and locking computational algorithms to detect cancer from bloodbased omics assays
    • Oversee day to day technical work of the team bringing to bear best practices from statistical / machine learning
    • Read and review the literature code releases patents and hardware/systems updates to keep abreast of current advancements in the fastmoving field of computational biology & ML
    • Develop solid understanding of inhouse assays and workflows sources of variation and data pipelines
    • Collaborate closely with peers in assay development clinical data science and software to advance performant models from research into a production environment

What youll bring to DELFI

    • PhD in Computer Science Computational biology/Bioinformatics Mathematics Statistics or EE
    • 5 years experience with a wide variety of classical and modern methods used in machine learning and AI (unsupervised semisupervised or supervised learning) as evidenced by strong publication record and/or algorithms released into production
    • Strong grasp of veridical data science explainable AI scientific measurement error sources of variation and best practices to control variation either experimentally or algorithmically
    • 5 years of industry experience in ML including at least 3 years experience in biotech pharma or diagnostics with increasing technical or managerial responsibility in a research or product development context
    • 5 years expertise programming in Python/R including modern ML frameworks (Tensorflow Pytorch or Jax) production compute environments (AWS/Nvidia) and versioning principles for reproducible modelbuilding and evaluation
    • Experience developing researchgrade algorithms based on biological data and collaborating with software teams to prioritize and move research efforts move to production
    • 3 of experience managing a team in a fastpaced environment with proven success delivering statistical models machine learning algorithms and results in pursuit of corporate objectives
    • Excellent mentor and manager with demonstrated ability to develop the career of junior scientists and engineers to inspire their best work
    • Collaborative passionate and driven with a cando attitude

What we offer fulltime employees

    • 100 paid medical dental and vision premiums for employees and dependents
    • 4 months fully paid parental leave
    • Flexible Time Off
    • 5 day winter break in December
    • A meaningful mission and strong company culture
$180000 $263000 a year
The total compensation for this role includes salary bonus equity and benefits. Actual compensation packages are based on a wide array of factors unique to each candidate including but not limited to skillset years & depth of experience certifications & relevant education geography.
We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race religion color national origin gender sexual orientation age marital status veteran status or disability status.

This position is not eligible for agency partnership. Resumes and outreach from staffing representatives will be declined.


Required Experience:

Director

Employment Type

Full-Time

Company Industry

About Company

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