Senior Principal Scientist Computational Systems Biology
Senior Principal Scientist Computational Systems Biology
Posted on :
06-04-2025
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1 Vacancy
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Job Description
About Us
Deep Genomics is at the forefront of using artificial intelligence to transform drug discovery. Our proprietary AI platform decodes the complexity of genome biology to identify novel drug targets mechanisms and therapeutics inaccessible through traditional methods. With expertise spanning machine learning bioinformatics data science engineering and drug development our multidisciplinary team in Toronto and Cambridge MA is revolutionizing how new medicines are created.
Where You Fit In
In this role you will be responsible for leveraging largescale genetic datasets to find potential targets and molecular mechanisms for oligonucleotide therapeutics. You will lead the development and implementation of analysis methods automated data processing and visualization pipelines for largescale omics data. You will organize the activities of bioinformatic scientists and data scientists and collaborate with other teams including statistical genetics ML science engineering and biology teams.
Key Requirements
- PhD in Computer Science Bioinformatics Genomics or related fields with at least 5 years of work experience preferably in industry setting
- Extensive experience with omic data processing and developing standardized processing and analysis pipelines e.g. transcriptomic proteomics datasets
- Experience with singlecell analyses including singlecell RNAseq data processing and analysis. Experience with additional technologies such as singlecell ATAC is nice to have
- Experience in visualization of complex genomic data and automated report generation
- Ability to perform differential expression gene coexpression or network analyses
- Strong scientific programming skills (Python preferred) and experience with highthroughput or cloud compute (especially GCP)
- Basic understanding of human genetics such as genomic regions and regulation (e.g. exons introns enhancers promoters transcription translation micrRNAs RNAbinding proteins etc.; basic understanding of human biology and disease
- Previous work experience in cardiometabolic or CNS diseases is desirable
- Familiarity with machine learning or AI models in the context of omics is an advantage but not required
- Previous experience in managing direct reports and/or external vendors is desirable
- Selfdriven with critical thinking intellectual curiosity and commitment to innovation
- Excellent communication and interpersonal skills
What we offer
- A collaborative and innovative environment at the frontier of computational biology machine learning and drug discovery.
- Highly competitive compensation including meaningful stock ownership.
- Comprehensive benefits including health vision and dental coverage for employees and families employee and family assistance program.
- Flexible work environment including flexible hours extended long weekends holiday shutdown unlimited personal days.
- Maternity and parental leave topup coverage as well as new parent paid time off.
- Focus on learning and growth for all employees learning and development budget & lunch and learns.
- Facilities located in the heart of Toronto the epicenter of machine learning and AI research and development and in Kendall Square Cambridge Mass. a global center of biotechnology and life sciences.
Deep Genomics welcomes and encourages applications from people with disabilities. Accommodations are available on request for candidates taking part in all aspects of the selection process.
Deep Genomics thanks all applicants however only those selected for an interview will be contacted.
Required Experience:
Staff IC
Employment Type
Full-Time
Key Skills
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