Job Title: Associate Scientist (JP9818 Location: Thousand Oaks CA. Employment Type: Contract Business Unit: Drug Substance Technologies Duration: 2 years (with likely extensions and/or conversion to permanent) Posting Date: 2/16/2022 Notes: 100 onsite; must have Bachelors degree in Chemistry or Chemical Engineering
3 Key Consulting is hiring an Associate Scientist for a consulting engagement with our direct client a leading global biopharmaceutical company.
Job Description: We are seeking a highly motivated individual to assist in our highthroughput experimentation (HTE) group and to support synthetics process development in Thousand Oaks CA. The candidate will work closely with our process chemists/chemical engineers to conduct highthroughput experiments and to assist with analytical data processing for highthroughput experiments. In addition to highthroughput support the position will support the of pressurized reactions reactors ranging from 0.05 mL to 5 L scales.
Support HighThroughput Experimentation in Synthetics Process Development:
Collaborate with process chemists/chemical engineers to execute and analyze highthroughput parallel experimentation (HTE) studies for the following:
Reaction screening/optimization for chemical reactions (catalysis biocatalysis and noncatalytic transformations).
Pressurized gas reactions.
Organic solvent extraction studies.
Metal scavenger/ remediation screenings.
Solubility studies of drug substance intermediates.
Crystallization studies of drug substances intermediates
Use various automation and analytical software/hardware to support THE.
Maintain good laboratory documentation practices and compliance with electronic laboratory notebook (ELN) guidelines
Laboratory Housekeeping/Management:
Coordinate with thirdparty vendors and our laboratory asset management service (LAMP) for preventative maintenance calibration and repair service of equipment and instruments
Initiate work orders when necessary to assist with setup of new equipment and/or remove obsolete/lifecycled equipment
Clean/decontaminate equipment and hood surfaces contaminated with hazardous materials
Maintain laboratory equipment and order replacement or addon parts/accessories as needed
Contact thirdparty vendors for information and quotes
Evaluate and document performance and reliability of lab equipment
Manage solid and liquid waste within synthetic laboratories per guidelines
Handle incoming/outgoing shipments of tools ancillary processing equipment and consumables and chemicals to remote client sites
Maintain good laboratory housekeeping and adhere to established organizational principles
Chemical Library Maintenance:
Order and organize laboratory reagents and consumables to support highthroughput experimentation
Ensure chemical library maintenance and reorder chemicals as needed
Maintain and update list of chemical inventories and ensure that the chemical and reagent inventory system (CRIS) is up to date.
Top Must Have Skills:
At least 1 year of research experience in chemistry laboratory.
Computer proficiency.
Must have Bachelors degree in Chemistry or Chemical Engineering.
Day to Day Responsibilities:
Follow procedure and perform laboratory experiments.
Maintain detailed records in electronic laboratory notebook.
Maintain chemical inventory and order chemicals as needed.
Organize laboratory space by following 5S.
Basic Qualifications:
Bachelors degree in chemistry or chemical engineering and experience in laboratory or manufacturing setting (academia or industry)
Strong scientific aptitude; attention to detail; technical problemsolving skills; and ability to multitask
Familiarity with good laboratory notebook documentation
Trained in basic laboratory safety
Preferred Qualifications:
Masters degree in chemistry or chemical engineering.
Academic and/or industrial experience working in a organic chemistry or chemical engineering laboratory.
Familiarity with automation computational chemistry and/or data analytics software such as LEA Spotfire Gaussian and Dynochem.
Familiarity with analytical instrumentation including HPLC GC and NMR spectroscopy.
Red Flags:
No laboratory experience.
Needs US Visa sponsorship.
Not available to work 5 days/week onsite.
Interview process: 1 h video interview with 10 min research talk by candidate
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