Precision Medicine Therapeutic Area Lead- Oncology

Career Category

Job Description

Join Amgens Mission of Serving Patients

At Amgen if you feel like youre part of something bigger its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980 weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology Inflammation General Medicine and Rare Disease we reach millions of patients each year. As a member of the Amgen team youll help make a lasting impact on the lives of patients as we research manufacture and deliver innovative medicines to help people live longer fuller happier lives.

Our awardwinning culture is collaborative innovative and science based. If you have a passion for challenges and the opportunities that lay within them youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Precision Medicine Therapeutic Area (TA) Lead Oncology

What you will do

Lets do this. Lets change the world. In this vital role you will act in conjunction with the Oncology Therapeutic Area head to advance the development and of Precision Medicine objectives. Lead a crossfunctional team to develop and implement translational and precision medicine strategies to support asset (and aboveasset as needed) development across the product lifecycle. Additionally partner with cross functional Therapeutic Area leads across Research & Development to guide the development of translational reverse translational and precision medicine strategies.

• Serve as the strategic integrator of various stakeholder inputs and multiple lines of evidence for the development of translational medicine and precision medicine strategies at asset and/or indication level.
• Set strategic vision to enhance the value of the asset across the product lifecycle through clinical biomarker target identification indication selection early indication of biological activity and patient stratification/selection including reverse translation strategies.
• Course correct as needed by incorporating deep mechanistic insights and omics signatures into actionable precision medicine strategies.
• Lead crossfunctional teams in the development and of phase appropriate integrated biomarker and human data plans to support translational pharmacology and inform patient selection strategies.
• Serve as the key liaison between research and development by providing clinical translational considerations (proof of target engagement dose selection patient selection) to inform discovery asset development as well as enabling reverse translational strategies (to gain mechanistic insights related to patient stratification response/resistance) for assets in clinical phase.
• Provide precision medicine considerations to shape disease area strategies (disease endotypes indications and combinatorial approaches). Provide subject matter expertise to inform registrational and access and use evidence generation plans.
• Work crossfunctionally to evaluate appropriate data sources and strategies for translational/precision medicine and propose funding/collaboration needs to appropriate Commercialization Governance Forums.

What we expect of you

We are all different yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications.

Basic Qualifications:

Doctorate degree and 4 years of proven experience

OR

Masters degree and 7 years of proven experience

OR

Bachelors degree and 9 years of proven experience

Preferred Qualifications:

• MD & PhD with 6 years industry & academic experience
• Deep scientific and analytical expertise in integrating multiple data sources e.g. omic clinical Real world evidence (RWE) to inform precision medicine approaches
• Strong professional network with external Key Opinion Leaders academic institutions and industry partners
• Experience in translational research and/or advancing clinical candidates
• Knowledge of Good Clinical Practices (GCP) and applicable regulatory requirements for biomarker and diagnostic development
• Proven ability to lead manage and motivate others in a complex multifunctional matrix environment
• Exceptional leadership and team management skills

What you can expect of us

As we work to develop treatments that take care of others we also work to care for your professional and personal growth and wellbeing. From our competitive benefits to our collaborative culture well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to relevant skills experience and qualifications.

In addition to the base salary Amgen offers a Total Rewards Plan based on eligibility comprising of health and welfare plans for staff and eligible dependents financial plans with opportunities to save towards retirement or other goals work/life balance and career development opportunities that may include:

• A comprehensive employee benefits package including a Retirement and Savings Plan with generous company contributions group medical dental and vision coverage life and disability insurance and flexible spending accounts
• A discretionary annual bonus program or for field sales representatives a salesbased incentive plan
• Stockbased longterm incentives
• Awardwinning timeoff plans
• Flexible work models including remote and hybrid work arrangements where possible

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

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Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

As an organization dedicated to improving the quality of life for people around the world Amgen fosters an inclusive environment of diverse ethical committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race color religion sex sexual orientation gender identity national origin protected veteran status disability status or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process to perform essential job functions and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Salary Range