drjobs Senior Scientist Cell Culture Fermentation Sciences

Senior Scientist Cell Culture Fermentation Sciences

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1 Vacancy
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Job Location drjobs

Gaithersburg, MD - USA

Hourly Salary drjobs

$ 112164 - 168246

Vacancy

1 Vacancy

Job Description

Senior Scientist (Cell Culture & Fermentation Sciences)

Introduction to the Group:

Join our Biopharmaceutical Development group a multidisciplinary scientific function providing expertise in Process/Analytical/Formulation/Device Development and Characterization. We are also responsible for transferring the processes to different commercial sites in and outside the AstraZeneca organization. Our Cell Culture and Fermentation Sciences Group is accountable for cell line development process development and process characterization. This group is also responsible for the scaleup and technical transfer of processes to different clinical and commercial sites and supports manufacturing deviations and regulatory submissions as needed.

Accountabilities:

As a Senior Scientist in the Cell Culture & Fermentation Sciences group you will work alongside a team of experienced bioprocess development scientists supporting projects across our portfolio.You will develop and optimize mammalian cell culture seed train bioreactor process and implement stateoftheart process technology including process analytical technology (PAT). You will also develop and improve cell culture media and nutrient feed. Your role will involve designing experiments and the statistical analysis of data. You will support technology transfers to clinical and commercial manufacturing sites including Contract Manufacturing Organizations (CMOs) and be responsible for authoring and reviewing development reports and contributing to regulatory filings such as IND and BLA. In addition you will engage with the Data Science and Modeling group to transform our ways of working identify areas for improvement in existing laboratory automation informatics tools and workflow using novel cell culture technologies. The position may require weekend work.

Education & Experience Requirements:

Education: BS MS or PhD in Chemical/Biochemical Engineering or related field

Experience: BS degree and 7 MS degree and 5 or a PhD and 0 years of relevant industry experience

Essential Skills:

  • Experience in cell culture and bioreactor operation

  • Strong background in experimental design and data analysis with the ability to evaluate and interpret complex data sets

  • Solid understanding of biochemical engineering concepts and biochemical pathways

  • Proficiency in Microsoft Office (or related) programs

  • Excellent collaboration and communication skills including proven technical writing skills

  • Capable of making independent decisions

  • Ability to handle multiple projects and / or tasks concurrently in a fastpaced environment

Desirable Skills:

  • Knowledge of design of experiment (DOE)

  • Data analysis and visualization using statistical analysis software such as JMP

  • Data analytics modeling simulation and prediction to improve process understanding

  • Experience using ambr bioreactor or similar high throughput tools

  • Experience and knowledge in multiple areas of focus (Robotics Informatics Machine Learning/AI IT)

When we put unexpected teams in the same room we unleash bold thinking with the power to inspire lifechanging medicines. Inperson working gives us the platform we need to connect work at pace and challenge perceptions. Thats why we work on average a minimum of three days per week from the office. But that doesnt mean were not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

At AstraZeneca we are dedicated to improving the lives of patients who need it the most. We are always moving forward searching for new solutions and embracing global opportunities. We value dedication motivation and courage. We are comfortable working in a risky and dynamic medicine development phase drawing from diverse minds to find the best path to success. We are always expanding our knowledge to get a broad perspective. It allows us to leverage and fuse our own skills with others to maximize impact. We are always improving supported by our leaders and team we have the freedom to work on initiatives that benefit ourselves the business and ultimately our patients.

Are you ready to make an incredible impact Join us at AstraZeneca where your work is recognized across the enterprise and externally too. Apply today!

The annual base pay (or hourly rate of compensation) for this position ranges from $112164 to $168246. Hourly and salaried nonexempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors including market location jobrelated knowledge skills and experience. In addition our positions offer a shortterm incentive bonus opportunity; eligibility to participate in our equitybased longterm incentive program (salaried roles) to receive a retirement contribution (hourly roles) and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program 401(k) plan; paid vacation and holidays; paid leaves; and health benefits including medical prescription drug dental and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired employee will be in an atwill position and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time including for reasons related to individual performance Company or individual department/team performance and market factors.

Date Posted

10Mar2025

Closing Date

14Mar2025Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion starting with our recruitment process. We welcome and consider applications from all qualified candidates regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations please complete the section in the application form.

Required Experience:

Senior IC

Employment Type

Full-Time

Company Industry

About Company

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