Senior Biotransformation Scientist
Senior Biotransformation Scientist
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Job Description
Are you a highly motivated biotransformation scientist with experience in metabolite identification using mass spectrometry Would you like to apply your expertise in a company that is accelerating innovative science and turning ideas into lifechanging medicines Join us to be part of the development of future treatments for Cardiovascular Renal and Metabolic diseases!
Working at AstraZeneca means being entrepreneurial thinking big and working together to make the impossible a reality. We are now recruiting a highly skilled and motivated biotransformation scientist to join the DMPK Drug Design and Biotransformation team within the Early Cardiovascular Renal and Metabolism (CVRM) therapeutic area at AstraZeneca. The position is based at AstraZenecas dynamic R&D site in Gothenburg Sweden
Accountabilities
As a Senior Biotransformation Scientist you will be part of a strong team at the forefront of DMPK science focusing on the biological fate of drug molecules in preclinical species and humans. This is a labbased role where you will study and elucidate mechanisms and pathways that determine the metabolism and disposition of drug substances. You are responsible for the identification of drug metabolites in biological samples and will provide significant input from target identification to lifecycle management.
In this role you will work in a team environment to support programs through the conduct of drug metabolism studies designed to understand biotransformation pathways and routes of elimination of diverse therapeutic modalities. Major responsibilities include planning conducting and documenting experiments designed to investigate metabolic pathways and structural elucidation of metabolites formed from new drug candidates.
Essential Skills/Experience
Proven ability of metabolite characterization using high resolution mass spectrometry and stateoftheart metabolite acquisition and processing software
PhD or equivalent degree in relevant discipline (Biotransformation Medicinal Chemistry Organic Chemistry or Analytical Chemistry)
Knowledge of biotransformation
Good understanding of in vitro and in vivo approaches used to understand drug metabolism issues
Ability to work independently and problem solve with an extensive track record of generating high quality data and reports
Scientific leadership evidenced by a publication track record
Good communication skills in English both verbal and in writing
The successful candidate is adaptable highly motivated and challengedriven with a history that demonstrates strong interpersonal skills that encourage successful collaborative working relationships.
Desirable Skills/Experience
Knowledge of guidelines and policies in drug development regarding biotransformation including MIST
Experience from industry environment
If your passion is science and you want to be part of a team that makes a bigger impact on patients lives then apply now!
Welcome with your application no later than March 23rd 2025.
Date Posted
11mars2025Closing Date
23mars2025Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion starting with our recruitment process. We welcome and consider applications from all qualified candidates regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations please complete the section in the application form.Required Experience:
Senior IC
Employment Type
Full-Time
