Executive Director Head of Hematology RD Translational Medicine
Executive Director Head of Hematology RD Translational Medicine
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1 Vacancy
Job Description
The Executive Director Hematology R&D Translational Medicine will report to the SVP Hematology R&D.
AstraZeneca is a global scienceled patientfocused biopharmaceutical company that focuses on the discovery development and commercialization of prescription medicines for some of the worlds most serious diseases. We are more than one of the worlds leading pharmaceutical companies.
AstraZeneca has a multifaceted environment that cultivates collaboration and innovation. We attract top minds and we nurture and build talent.
Within Hematology R&D we are committed to advancing science to deliver lifechanging medicines to patients most in need. With a combinationfocused pipeline that exploits the power of six scientific platforms (ImmunoOncology Tumor Drivers and Resistance DNA Damage Response Antibodydrug Conjugates Cell Therapy and Epigenetics) to help address unmet clinical needs in a host of hematological cancers we are motivated by a dedication to the scientific discovery and collaboration that will one day help eliminate cancer as a cause of death. This unit has responsibility for the value chain from discovery through to latestage development enabling rapid acceleration of promising earlystage assets and lifecycle management programs.
The Hematology Research and Development (R&D) team is accountable for all drug development activities in hematology research from firstinman studies all the way to latestage trials leading to drug approval by regulatory agencies (Phase 1 2 and 3 trials). The team strives to deliver compelling preclinical clinical and translational data packages providing confidence in the dosing strategy tolerability profile and therapeutic efficacy of our candidate to support investment in latestage clinical development leading to drug approval.
Key responsibilities include:
- Leading HematologicalOncology and Minimal Residual Disease (MRD) initiatives.
- Developing and implementing biomarker strategies and patient selection biomarkers.
- Ensuring datadriven clinical translational strategies for target validation.
- Supporting early and latestage hematologyoncology projects and developing HemOnc biomarker tools.
- Building relationships with senior scientific staff and aligning with AstraZenecas mission.
- Representing Hematology R&D Translational Team at executive levels.
- Managing and prioritizing the research and early development pipeline.
- Supporting early clinical PoC and development phases.
- Collaborating with the clinical development team to design and execute appropriate phase 1/2a study(s) to generate FIH safety PK PD PK/PD biomarker or efficacy/PoC data to support continued clinical development or nogo for program
- Building strong relationships with opinion leaders scientific advisors alliance partners and patient advocacy groups to help drive the scientific communications program and to ensure that team meets scientific and business objective
- Oversee & manage the Hematology Translational Medicine organization of 40 Translational Scientists and Translational Medicine Leaders.
Experience and Required Skills:
- PhD MD or DVM with a minimum of 10 years of relevant experience.
- Strong scientific methodology communication and presentation skills.
- Ability to manage multiple research and development programs.
- Ability to constructively facilitate debate across deep technical and broad strategic issues and develop alternative options
- Ability to create an environment where imaginative and constructive dialog can flourish and manage conflict n
- Attract retain manage coach and mentor scientific staff
Date Posted
15Jan2025Closing Date
30Mar2025Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion starting with our recruitment process. We welcome and consider applications from all qualified candidates regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations please complete the section in the application form.Required Experience:
Director
Employment Type
Full-Time
